F
Fanny Chui Fun Ip
Researcher at Hong Kong University of Science and Technology
Publications - 25
Citations - 261
Fanny Chui Fun Ip is an academic researcher from Hong Kong University of Science and Technology. The author has contributed to research in topics: Neuroprotection & Receptor. The author has an hindex of 8, co-authored 25 publications receiving 222 citations.
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Journal ArticleDOI
Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management.
Fanny Chui Fun Ip,Yu Pong Ng,Hui Jin An,Ying Dai,Hai Hong Pang,Yue Qing Hu,Allison C. Chin,Calvin B. Harley,Yung Hou Wong,Nancy Y. Ip +9 more
TL;DR: It is demonstrated that CAG stimulates telomerase activity and cell proliferation in human neonatal keratinocytes and rat neuronal cells, and induces CREB activation followed by tert and bcl2 expression, and may have a novel therapeutic role in depression.
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Highly trans‐Selective Arylation of Achmatowicz Rearrangement Products by Reductive γ‐Deoxygenation and Heck–Matsuda Reaction: Asymmetric Total Synthesis of (−)‐Musellarins A–C and Their Analogues
TL;DR: A new two-step trans arylation of AR products to access 2,6-trans-dihydropyranones is reported, demonstrated in the first asymmetric total synthesis of (-)-musellarins A-C and 12 analogues in 11-12 steps.
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Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton
Yuewen Chen,Fanny Chui Fun Ip,Lei Shi,Lei Shi,Zhe Zhang,Huibin Tang,Yu Pong Ng,Wen-Cai Ye,Amy K.Y. Fu,Nancy Y. Ip +9 more
TL;DR: Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering through modulating the interaction between receptors and the actin cytoskeletal network.
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Neuroprotective effect of a novel Chinese herbal decoction on cultured neurons and cerebral ischemic rats
Fanny Chui Fun Ip,Yu Ming Zhao,Yu Ming Zhao,Kim Wan Chan,Elaine Yee Ling Cheng,Estella P.S. Tong,Oormila Chandrashekar,Guang Miao Fu,Zhongzhen Zhao,Nancy Y. Ip +9 more
TL;DR: PSR is neuroprotective both in vitro and in vivo – it protects cultured neurons against NMDA excitotoxicity, and effectively reduces ischemic injury and neurobehavioral deficit in MCAO rats in both the pre- and post-treatment regimens.
Journal ArticleDOI
Olean-12-eno[2,3-c] [1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell lines.
TL;DR: OEOA significantly reduces cell proliferation without inducing cell death in three types of leukemia cell lines, including K562, HEL and Jurket, and is identified as a novel chemical entity for further development as therapeutics against leukemia.