Farhad Imam

TL;DR: These studies define major characteristics of the transcriptional programs that underlie the life cycle, compare development in males and females, and show that large-scale gene expression data collected from whole animals can be used to identify genes expressed in particular tissues and organs or genes involved in specific biological and biochemical processes.

TL;DR: In this paper, the genomic locations of histone H3 molecules bearing lysine trimethylation modifications before and after the maternal-zygotic transition in zebrafish were mapped to study the changes in chromatin structure that accompany pluripotency and genome activation.

TL;DR: Two classes of EcR mutations are identified and molecularly mapped: those specific to EcR-B1 that uncouple metamorphosis, and embryonic-lethal mutations that map to common sequences encoding the DNA- and ligand-binding domains.

TL;DR: The results suggest that stumps function promotes FGF-directed cell migrations, either by potentiating the FGF signaling process or by coupling the signal to the cellular machinery required for directed cell movement.

TL;DR: A computational method is presented that leverages the peer-reviewed literature in the automatic analysis of gene expression data sets with different properties and is able to rapidly define and identify the biologically relevant gene expression profiles without manual intervention.