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Farhat Afrin
Researcher at Taibah University
Publications - 64
Citations - 2784
Farhat Afrin is an academic researcher from Taibah University. The author has contributed to research in topics: Leishmania donovani & Antigen. The author has an hindex of 32, co-authored 64 publications receiving 2511 citations. Previous affiliations of Farhat Afrin include Jamia Hamdard & Indian Institute of Chemical Biology.
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Mesenchymal stem cell-based therapy: a new paradigm in regenerative medicine.
Neeraj Kumar Satija,Vimal Kishor Singh,Yogesh Verma,Pallavi Gupta,Shilpa Sharma,Farhat Afrin,Menka Sharma,Pratibha Sharma,R. P. Tripathi,Gangenahalli U. Gurudutta +9 more
TL;DR: MSC transplantation, genetically modified MSC‐based therapy, tissue engineering using MSCs, and challenges and future prospects are reviewed.
Journal ArticleDOI
Mesenchymal Stem Cells: Molecular Targets for Tissue Engineering
Neeraj Kumar Satija,Gangenahalli U. Gurudutta,Shilpa Sharma,Farhat Afrin,Pallavi Gupta,Yogesh Verma,Vimal Kishor Singh,Rajendra P. Tripathi +7 more
TL;DR: Improved expansion as well as osteogenic differentiation of MSCs can be attained using a combinatorial approach involving co-expression of proliferation and differentiation genes, however, a thorough understanding of the molecular mechanism is necessary for enhancing the self-renewal ability and osteogenic potential in vitro.
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In vitro antifungal activity of hydroxychavicol isolated from Piper betle L
Intzar Ali,Farrah Gul Khan,Krishan Avtar Suri,Bishan Datt Gupta,Naresh Kumar Satti,Prabhu Dutt,Farhat Afrin,Ghulam Nabi Qazi,Inshad Ali Khan +8 more
TL;DR: The antifungal activity exhibited by hydroxychavicol warrants its use as an antIFungal agent particularly for treating topical infections, as well as gargle mouthwash against oral Candida infections.
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Stromal-Derived Factor-1/CXCR4 Signaling: Indispensable Role in Homing and Engraftment of Hematopoietic Stem Cells in Bone Marrow
TL;DR: Current knowledge of the mechanisms through which SDF-1/CXCR4 signaling promotes restoration of hematopoiesis by regulating the homing and engraftment of HSPCs are presented.
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Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo.
Sylvie Bertholet,Romina S. Goldszmid,Alexandre Morrot,Alain Debrabant,Farhat Afrin,Carmen M. Collazo-Custodio,Mathieu Houde,Michel Desjardins,Alan Sher,David B. Sacks +9 more
TL;DR: Leishmania Ags appear to be confined to an intraphagosomal processing pathway that requires higher concentrations of Ags, suggesting that these parasites may have evolved strategies to impair the efficient endoplasmic reticulum-based, TAP-dependent cross-presentation pathway to avoid or delay CD8+ T cell priming.