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Faustino Mollinedo

Researcher at Spanish National Research Council

Publications -  231
Citations -  21625

Faustino Mollinedo is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Edelfosine & Apoptosis. The author has an hindex of 56, co-authored 228 publications receiving 18565 citations. Previous affiliations of Faustino Mollinedo include University of Salamanca & University of Valladolid.

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Journal ArticleDOI

A monoclonal antibody to CD11c antigen inhibits the production of superoxide anion induced by concanavalin A in PMA-differentiated U-937 cells.

TL;DR: Findings suggest that the CD11c antigen is involved in the triggering of the respiratory burst response by mononuclear phagocytic cells.
Book ChapterDOI

Lipid Raft Isolation by Sucrose Gradient Centrifugation and Visualization of Raft-Located Proteins by Fluorescence Microscopy: The Use of Combined Techniques to Assess Fas/CD95 Location in Rafts During Apoptosis Triggering.

TL;DR: Two protocols are provided that support the presence of Fas/CD95 in lipid rafts during apoptosis, involving lipid raft isolation and confocal microscopy techniques and can be extended to any protein of interest to be analyzed for its association to lipid rafting.
Journal ArticleDOI

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells.

TL;DR: Novel molecular insights are provided into the identification of miRNAs regulating granulocytic differentiation of human leukemia cells and normal CD34+-hematopoietic progenitor/stem cells, and may assist in the development of novel miRNA-targeted therapies for leukemia.
Journal ArticleDOI

Genomic organization, chromosomal localization, alternative splicing, and isoforms of the human synaptosome-associated protein-23 gene implicated in vesicle-membrane fusion processes.

TL;DR: The full-length human cDNA and the SNAP23 gene, a component of the cellular mechanism required for specific membrane fusion and targetting of intracellular vesicles, are cloned and interact in vitro with human syntaxin 6, thus retaining the specific protein interaction required for membrane fusion.