Mycobacterium species have long been recognised as a significant source of morbidity and mortality in finfish aquaculture, as well as in wild finfishes. Mycobacteria infecting fishes also include zoonotic pathogens that can cause protracted illness, especially in immunocompromised individuals. Several basic aspects of mycobacterial pathobiology in aquatic animals remain poorly understood, although a number of important recent developments have been made, especially with respect to identification of novel Mycobacterium spp. infecting fishes and a new group of mycobacteria closely related to the human pathogen Mycobacterium ulcerans. This review will encompass important aspects of mycobacterial disease in fishes, discuss recent research including studies of mycobacteriosis in striped bass (Morone saxatilis) of Chesapeake Bay, USA, and suggest directions for future work.

http://www.bfm21.com/download/latin/2.pdf

Mycobacteriosis in fishes: a review.

Post-weaning multisystemic wasting syndrome (PMWS) emerged as a significant disease affecting pig production in the 1990s although the causal agent, porcine circovirus type 2 (PCV2), and the disease itself, had existed in swine for many years prior to this. The important multifactorial 'triggers' of PMWS include the immune and infection status of the sow, the timing of PCV2 infection, variations in the virulence of PCV2, co-infections, immune modulation as well as host genetics and management factors. In terms of diagnosis, histopathological examination and the detection of PCV2 within lymphoid tissue remains the 'gold standard' as quantitative PCR techniques are currently not specific or sensitive enough. The recent commercial availability of PCV2 vaccines provides an excellent tool for reducing the impact of PMWS and other porcine circovirus-related diseases. This review assesses recent advances in the epidemiology, diagnosis and control of PMWS.

Recent advances in the epidemiology, diagnosis and control of diseases caused by porcine circovirus type 2

SM holds a Ramon y Cajal postdoctoral contract from the Spanish Ministry of Economy and Competitiveness (MINECO) and is supported by the European Commission Marie Curie Actions (FP7-PEOPLE-2010-RG, Project No. 274184). BC and SE are supported by Fundacao para a Ciencia e a Tecnologia, Portugal (SFRH/BPD/77210/2011 and SFRH/BPD/49051/2008, respectively).

https://digital.csic.es/bitstream/10261/144229/4/New%20developments%20and%20biological%20insights-Morais%202016%20RAQ.pdf

New developments and biological insights into the farming of Solea senegalensis reinforcing its aquaculture potential

Concurrent infections are important for expression of porcine circovirus associated disease.

Hepatitis E virus (HEV) causes self-limiting acute hepatitis in humans that can eventually result in acute liver failures or progress to chronic infections. While in tropical and sub-tropical areas, HEV infections are associated with important waterborne epidemics, in Northern countries, HEV infections are autochthonous with a zoonotic origin. In the past decade, it has become clear that certain HEV genotypes are zoonotic and that swine, and more generally Suidae, are the main reservoir. Zoonotic transmissions of the virus may occur via direct contact with infected pigs, wild boars or consumption of contaminated meat. This review describes the current knowledge on domestic and wild Suidae as reservoirs of HEV and the evidence of the different routes of HEV transmission between these animals and humans.

/pdf/recent-knowledge-on-hepatitis-e-virus-in-suidae-reservoirs-3xkmudojfq.pdf

Recent knowledge on hepatitis E virus in Suidae reservoirs and transmission routes to human.

Molecular epidemiology of canine adenovirus type 1 and type 2 in free-ranging red foxes (Vulpes vulpes) in Italy

Hepatitis E is an acute human disease caused by the hepatitis E virus (HEV). In addition to humans, HEV has been detected in several animal species and is recognized as a zoonotic pathogen. Pigs, wild boar and deer can be reservoir. In this study, we evaluated HEV prevalence in a free-living red deer (Cervus elaphus) population in central Italy by detecting virus-specific antibodies and RNA in sera. A total of 35 of 251 red deer sera were positive for anti-HEV IgG. HEV RNA was detected in 10 of 91 sera examined. Two genomic fragments targeted by diagnostic PCRs in the capsid region were sequenced, both matching with genotype 3 HEV. Overall results confirmed the occurrence of HEV infection in deer also in Italy.

Presence of Hepatitis E Virus in a RED Deer (Cervus elaphus) Population in Central Italy

Virulent feline calicivirus disease in a shelter in Italy: a case description.

Ten Cases of Feline Mesothelioma: an Immunohistochemical and Ultrastructural Study

Deciduoid mesothelioma is a rare variant of epithelial mesothelioma, up to now only described in human pathology, which bears remarkable cytomorphologic resemblance to the endometrium of pregnancy, termed decidua. A case of peritoneal mesothelioma with deciduoid features in a 10-year-old, female dog is reported. Multiple whitish-gray nodules (1-5 mm in diameter) in parietal peritoneum and mesentery were histologically composed of large, proliferating, polygonal or ovoid cells with an abundant eosinophilic, glassy cytoplasm. Immunohistochemical evaluation indicated that the neoplastic cells coexpressed cytokeratin and vimentin with strong and diffuse cytoplasmic staining, and ultrastructural analysis showed long and slender mesothelial-type microvilli; these findings confirmed the mesothelial origin of the tumor.

https://journals.sagepub.com/doi/pdf/10.1354/vp.43-2-198

Federico Morandi

Papers

Molecular epidemiology of canine adenovirus type 1 and type 2 in free-ranging red foxes (Vulpes vulpes) in Italy

Presence of Hepatitis E Virus in a RED Deer (Cervus elaphus) Population in Central Italy

Virulent feline calicivirus disease in a shelter in Italy: a case description.

Ten Cases of Feline Mesothelioma: an Immunohistochemical and Ultrastructural Study

Deciduoid Peritoneal Mesothelioma in a Dog