F
Fei Mao
Researcher at Jiangsu University
Publications - 93
Citations - 4371
Fei Mao is an academic researcher from Jiangsu University. The author has contributed to research in topics: Mesenchymal stem cell & Cancer. The author has an hindex of 27, co-authored 73 publications receiving 2898 citations.
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Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro
Ying Zhou,Huitao Xu,Wenrong Xu,Bingying Wang,Huiyi Wu,Yang Tao,Bin Zhang,Mei Wang,Fei Mao,Yongmin Yan,Shuo Gao,Hongbing Gu,Wei Zhu,Hui Qian +13 more
TL;DR: The results in the present study indicate that hucMSC-ex can repair cisplatin-induced AKI in rats and NRK-52E cell injury by ameliorating oxidative stress and cell apoptosis, promoting cell proliferation in vivo and in vitro.
Journal ArticleDOI
Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving β-Cell Destruction.
Yaoxiang Sun,Hui Shi,Siqi Yin,Cheng Ji,Xu Zhang,Bin Zhang,Peipei Wu,Yinghong Shi,Fei Mao,Yongmin Yan,Wenrong Xu,Hui Qian +11 more
TL;DR: Exosomes from hucMSC can alleviate type 2 DM by reversing peripheral insulin resistance and relieving β-cell destruction, providing an alternative approach for T2DM treatment.
Journal ArticleDOI
Human mesenchymal stem cells isolated from the umbilical cord.
Chun Qiao,Wenrong Xu,Wei Zhu,Jiabo Hu,Hui Qian,Qing Yin,Runqiu Jiang,Yongmin Yan,Fei Mao,Huan Yang,Xingzhong Wang,Yongchang Chen +11 more
TL;DR: It is shown that umbilical cords may be a novel alternative source of human MSCs for experimental and clinical applications and exhibited multi‐potential differentiation into osteogenic and adipogenic cells.
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hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury
Yongmin Yan,Wenqian Jiang,Youwen Tan,Shengqiang Zou,Hongguang Zhang,Fei Mao,Aihua Gong,Hui Qian,Wenrong Xu +8 more
TL;DR: Human umbilical cord MSC-derived exosome (hucMSC-Ex) administrated by tail vein or oral gavage at different doses and, in engrafted liver mouse models, noted antioxidant and anti-apoptotic effects and rescue from liver failure.
Journal ArticleDOI
Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-β/Smad pathway.
Jianmei Gu,Hui Qian,Li Shen,Xu Zhang,Wei Zhu,Ling Huang,Yongmin Yan,Fei Mao,Chonghui Zhao,Yunyan Shi,Wenrong Xu +10 more
TL;DR: The results suggest that gastric cancer cells triggered the differentiation of hucMSCs to CAFs by exosomes-mediated TGF-β transfer and T GF-β/Smad pathway activation, which may represent a novel mechanism for MSCs toCAFs transition in cancer.