H
Hui Qian
Researcher at Jiangsu University
Publications - 219
Citations - 13377
Hui Qian is an academic researcher from Jiangsu University. The author has contributed to research in topics: Mesenchymal stem cell & Cancer. The author has an hindex of 50, co-authored 175 publications receiving 9481 citations. Previous affiliations of Hui Qian include Shanghai Jiao Tong University.
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Journal ArticleDOI
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Liver Fibrosis
Tingfen Li,Yongmin Yan,Bingying Wang,Hui Qian,Xu Zhang,Li Shen,Mei Wang,Ying Zhou,Wei Zhu,Wei Li,Wenrong Xu +10 more
TL;DR: Results suggest that hucMSC-Ex could ameliorate CCl4-induced liver fibrosis by inhibiting EMT and protecting hepatocytes, which provides a novel approach for the treatment of fibrotic liver disease.
Journal ArticleDOI
Exosomes in cancer: small particle, big player
TL;DR: The multifaceted roles of exosomes, the small secreted particles, in communicating with other cells within tumor microenvironment are reviewed, suggesting they may provide promising biomarkers for cancer diagnosis and represent new targets for cancer therapy.
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HucMSC-Exosome Mediated-Wnt4 Signaling Is Required for Cutaneous Wound Healing.
Bin Zhang,Mei Wang,Aihua Gong,Xu Zhang,Xiaodan Wu,Yanhua Zhu,Hui Shi,Lijun Wu,Wei Zhu,Hui Qian,Wenrong Xu +10 more
TL;DR: It is found that hucMSC‐Ex‐treated wounds exhibited significantly accelerated re‐epithelialization, with increased expression of CK19, PCNA, collagen I (compared to collagen III) in vivo.
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Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro
Ying Zhou,Huitao Xu,Wenrong Xu,Bingying Wang,Huiyi Wu,Yang Tao,Bin Zhang,Mei Wang,Fei Mao,Yongmin Yan,Shuo Gao,Hongbing Gu,Wei Zhu,Hui Qian +13 more
TL;DR: The results in the present study indicate that hucMSC-ex can repair cisplatin-induced AKI in rats and NRK-52E cell injury by ameliorating oxidative stress and cell apoptosis, promoting cell proliferation in vivo and in vitro.
Journal ArticleDOI
Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo
Wei Zhu,Ling Huang,Yahong Li,Xu Zhang,Jianmei Gu,Yongmin Yan,Xiaomeng Xu,Mei Wang,Hui Qian,Wenrong Xu +9 more
TL;DR: A new mechanism through which MSC-exosome-mediated cell-cell interactions may contribute to tumor progression is demonstrated, which is demonstrated through which inhibition of ERK1/2 activation reserved the increase of VEGF level by MSC -exosomes.