F
Felipe Samaniego
Researcher at University of Texas MD Anderson Cancer Center
Publications - 243
Citations - 8128
Felipe Samaniego is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Rituximab & Follicular lymphoma. The author has an hindex of 41, co-authored 232 publications receiving 6732 citations.
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Journal ArticleDOI
High Rate of Durable Remissions After Treatment of Newly Diagnosed Aggressive Mantle-Cell Lymphoma With Rituximab Plus Hyper-CVAD Alternating With Rituximab Plus High-Dose Methotrexate and Cytarabine
Jorge E. Romaguera,Luis Fayad,Maria A Rodriguez,Kristine Broglio,Frederick B. Hagemeister,Barbara Pro,Peter McLaughlin,Anas Younes,Felipe Samaniego,Andre Goy,Andreas H. Sarris,Nam H. Dang,Michael Wang,Virginia Beasley,L. Jeffrey Medeiros,Ruth L. Katz,Harish Gagneja,Barry I. Samuels,Terry L. Smith,Fernando Cabanillas +19 more
TL;DR: Rituximab plus hyper-CVAD alternating with rituxIMab plus high-dose methotrexate and cytarabine is effective in untreated aggressive MCL and toxicity is significant but expected.
Journal ArticleDOI
Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial
Jason R. Westin,Fuliang Chu,Min Zhang,Luis Fayad,Larry W. Kwak,Nathan Fowler,Jorge E. Romaguera,Fredrick B. Hagemeister,Michelle A. Fanale,Felipe Samaniego,Lei Feng,Veerabhadran Baladandayuthapani,Zhiqiang Wang,Wencai Ma,Yanli Gao,Michael J. Wallace,Luis M Vence,Laszlo Radvanyi,Tariq Muzzafar,Rinat Rotem-Yehudar,R. Eric Davis,Sattva S. Neelapu +21 more
TL;DR: The combination of pidilizumab and rituximab was well tolerated, with no autoimmune or treatment-related adverse events of grade 3 or 4, and the results suggest that immune checkpoint blockade is worthy of further study in follicular lymphoma.
Journal ArticleDOI
Double hit lymphoma: the MD Anderson Cancer Center clinical experience.
Yasuhiro Oki,Mansoor Noorani,Pei Lin,Richard E. Davis,Sattva S. Neelapu,Long Ma,Mohamed Amin Ahmed,Maria Alma Rodriguez,Fredrick B. Hagemeister,Nathan Fowler,Michael Wang,Michelle A. Fanale,Loretta J. Nastoupil,Felipe Samaniego,Hun J. Lee,Bouthaina S. Dabaja,Chelsea C. Pinnix,L. J. Medeiros,Yago Nieto,Issa F. Khouri,Larry W. Kwak,Francesco Turturro,Jorge E. Romaguera,Luis Fayad,Jason R. Westin +24 more
TL;DR: Multivariate analysis identified performance status ≥2 and bone marrow involvement as independent adverse prognostic factors for EFS and OS and further research is needed to identify predictive and/or targetable biological markers and novel therapeutic approaches for DHL patients.
Journal ArticleDOI
Eight-year experience with allogeneic stem cell transplantation for relapsed follicular lymphoma after nonmyeloablative conditioning with fludarabine, cyclophosphamide, and rituximab.
Issa F. Khouri,Peter McLaughlin,Rima M. Saliba,Chitra Hosing,Martin Korbling,Ming S. Lee,L. Jeffrey Medeiros,Luis Fayad,Felipe Samaniego,Amin M. Alousi,Paolo Anderlini,Daniel R. Couriel,Marcos de Lima,Sergio Giralt,Sattva S. Neelapu,Naoto T. Ueno,Barry I. Samuels,Fredrick B. Hagemeister,Larry W. Kwak,Richard E. Champlin +19 more
TL;DR: The described results are a step forward toward developing a curative strategy for recurrent follicular lymphoma and all 18 patients who were tested and had evidence of JH/bcl-2 fusion transcripts in the bone marrow at study entry experienced continuous molecular remission.
Journal ArticleDOI
Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: a phase 1/2 clinical trial
Michael Wang,Luis Fayad,Nicolaus A. Wagner-Bartak,Liang Zhang,Fredrick Hagemeister,Sattva S. Neelapu,Felipe Samaniego,Peter McLaughlin,Michelle A. Fanale,Anas Younes,Fernando Cabanillas,Nathan Fowler,Kate J. Newberry,Luhong Sun,Ken H. Young,Richard E. Champlin,Larry W. Kwak,Lei Feng,Maria Badillo,Maria Teresa Bejarano,Kimberly Hartig,Wendy Chen,Yiming Chen,Catriona Byrne,Neda Bell,Jerome B. Zeldis,Jorge E. Romaguera +26 more
TL;DR: Oral lenalidomide plus rituximab is well tolerated and effective for patients with relapsed or refractory MCL and the primary efficacy endpoint was overall response (complete or partial response).