F
Fernando Martínez
Researcher at University of Concepción
Publications - 37
Citations - 989
Fernando Martínez is an academic researcher from University of Concepción. The author has contributed to research in topics: Ascorbic acid & GLUT1. The author has an hindex of 14, co-authored 37 publications receiving 815 citations.
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Journal ArticleDOI
Differential subcellular distribution of glucose transporters GLUT1–6 and GLUT9 in human cancer: Ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissues
Alejandro Godoy,Viviana Ulloa,Federico Rodríguez,Karin Reinicke,Alejandro J. Yáñez,María de los Angeles García,Rodolfo A. Medina,Monica A. Carrasco,Sofía Barberis,Tamara Castro,Fernando Martínez,Ximena Koch,Juan Carlos Vera,María Teresa Poblete,Carlos D. Figueroa,Bruno Peruzzo,Fernando Pérez,Francisco Nualart +17 more
TL;DR: The extensive expression of GLUT2 and 5 (glucose/fructose and fructose transporters, respectively) in malignant human tissues indicates that fructose may be a good energy substrate in tumor cells and suggest that fructose uptake could be used for positron emission tomography imaging.
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Vitamin C uptake and recycling among normal and tumor cells from the central nervous system.
Allisson Astuya,Teresa Caprile,Maite A. Castro,Katterine Salazar,María de los Angeles García,Karin Reinicke,Federico Rodríguez,Juan Carlos Vera,Carola Millán,Viviana Ulloa,Marcela Low,Fernando Martínez,Francisco Nualart +12 more
TL;DR: Functional uptake analyses support the hypothesis that astrocytes are involved in vitamin C recycling in the nervous system by avoiding the hydrolysis of dehydroascorbic acid produced by antioxidative protection.
Journal ArticleDOI
Brain Glucose-Sensing Mechanism and Energy Homeostasis.
Antonio J. López-Gambero,Antonio J. López-Gambero,Fernando Martínez,Katterine Salazar,Manuel Cifuentes,Francisco Nualart +5 more
TL;DR: The aim of this review focuses on integrating the current understanding of various glucose-sensing mechanisms described in the brain, thereby establishing a relationship between neuroanatomy and control of physiological processes involved in both metabolic and energy balance.
Journal ArticleDOI
Vitamin C Transporters, Recycling and the Bystander Effect in the Nervous System: SVCT2 versus Gluts.
Francisco Nualart,Mack L,Andrea García,Pedro Cisternas,Ernesto R. Bongarzone,Heitzer M,Nery Jara,Fernando Martínez,Luciano Ferrada,Francisca Espinoza,Baeza,Katterine Salazar +11 more
TL;DR: This review will compare the molecular and structural aspects of vitamin C and glucose transporters and their expression in endothelial or choroid plexus cells, which form part of the blood-brain barrier and blood-cerebrospinal fluid (CSF) barrier, respectively and describe SVCT and GLUT expression in different cells of the brain.
Journal ArticleDOI
Glial glucokinase expression in adult and post-natal development of the hypothalamic region
Carola Millán,Fernando Martínez,Christian Cortés-Campos,Isabel Lizama,María José Yañez,Paula Llanos,Karin Reinicke,Federico Rodríguez,Bruno Peruzzo,Francisco Nualart,María de los Angeles García +10 more
TL;DR: Tanycytes mediate, at least in part, the mechanism by which the hypothalamus detects changes in glucose concentrations, as demonstrated by Western-blot analysis, QRT–PCR and in situ hybridization.