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Katterine Salazar

Researcher at University of Concepción

Publications -  35
Citations -  649

Katterine Salazar is an academic researcher from University of Concepción. The author has contributed to research in topics: Ascorbic acid & Dehydroascorbic acid. The author has an hindex of 13, co-authored 29 publications receiving 505 citations.

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Vitamin C uptake and recycling among normal and tumor cells from the central nervous system.

TL;DR: Functional uptake analyses support the hypothesis that astrocytes are involved in vitamin C recycling in the nervous system by avoiding the hydrolysis of dehydroascorbic acid produced by antioxidative protection.
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Brain Glucose-Sensing Mechanism and Energy Homeostasis.

TL;DR: The aim of this review focuses on integrating the current understanding of various glucose-sensing mechanisms described in the brain, thereby establishing a relationship between neuroanatomy and control of physiological processes involved in both metabolic and energy balance.
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Vitamin C Transporters, Recycling and the Bystander Effect in the Nervous System: SVCT2 versus Gluts.

TL;DR: This review will compare the molecular and structural aspects of vitamin C and glucose transporters and their expression in endothelial or choroid plexus cells, which form part of the blood-brain barrier and blood-cerebrospinal fluid (CSF) barrier, respectively and describe SVCT and GLUT expression in different cells of the brain.
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The Na+-dependent L-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids.

TL;DR: The data demonstrates that brain cortex and cerebellar stem cells, neurons and neuroblastoma cells express SVCT2, and the ability of different flavonoids to inhibit AA uptake in normal or immortalized neurons is shown.
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The oxidized form of vitamin C, dehydroascorbic acid, regulates neuronal energy metabolism

TL;DR: DHA is a novel modulator of neuronal energy metabolism by facilitating the utilization of glucose through the PPP for antioxidant purposes by stimulating the rate of lactate uptake by neurons in a time‐ and dose‐dependent manner.