F
Fernando Remião
Researcher at University of Porto
Publications - 201
Citations - 7109
Fernando Remião is an academic researcher from University of Porto. The author has contributed to research in topics: Oxidative stress & Chemistry. The author has an hindex of 42, co-authored 172 publications receiving 5900 citations. Previous affiliations of Fernando Remião include University of Aveiro & Universidade Nova de Lisboa.
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Journal ArticleDOI
Paraquat Poisonings: Mechanisms of Lung Toxicity, Clinical Features, and Treatment
Ricardo Jorge Dinis-Oliveira,José Alberto Duarte,Amparo Sánchez-Navarro,Fernando Remião,Maria de Lourdes Bastos,Félix Carvalho +5 more
TL;DR: The most pertinent and significant findings published in established scientific publications since the discovery of PQ are collected and described, focusing on the most recent developments related to PQ lung toxicity and their relevance to the treatment of human poisonings.
Journal ArticleDOI
Toxicity of amphetamines: an update
Márcia Carvalho,Helena Carmo,Vera Marisa Costa,João Paulo Capela,Helena Pontes,Fernando Remião,Félix Carvalho,Maria de Lourdes Bastos +7 more
TL;DR: The long-studied classical amphetamines—amphetamine itself, as well as methamphetamine and MDMA provide plenty of data that may be useful to predict toxicological outcome to improvident abusers and are for that reason the main focus of this review.
Journal ArticleDOI
Paraquat exposure as an etiological factor of Parkinson's disease.
Ricardo Jorge Dinis-Oliveira,Fernando Remião,Helena Carmo,José Alberto Duarte,A. Sánchez Navarro,Maria de Lourdes Bastos,Félix Carvalho +6 more
TL;DR: PQ-induced lipid peroxidation and consequent cell death of dopaminergic neurons can be responsible for the onset of the Parkinsonian syndrome, thus indicating that this herbicide may induce PD or influence its natural course.
Journal ArticleDOI
Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview.
João Paulo Capela,Helena Carmo,Fernando Remião,Maria de Lourdes Bastos,Andreas Meisel,Félix Carvalho +5 more
TL;DR: The main aim of this review was to contribute to the understanding of the cellular and molecular mechanisms involved in MDMA neurotoxicity, which can help in the development of therapeutic approaches to prevent or treat the long-term neuropsychiatric complications of MDMA abuse in humans.
Journal ArticleDOI
Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy
Renata Silva,Vânia Vilas-Boas,Helena Carmo,Ricardo Jorge Dinis-Oliveira,Ricardo Jorge Dinis-Oliveira,Félix Carvalho,Maria de Lourdes Bastos,Fernando Remião +7 more
TL;DR: In this review, a new focus is brought on the therapeutic interest of inducing and/or activating P-gp for limiting the toxicity caused by its substrates, and several in vivo and in vitro studies validating the use of such a therapeutic strategy are discussed.