F
Fiona Sait
Researcher at Laboratory of Molecular Biology
Publications - 1
Citations - 476
Fiona Sait is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Ligand (biochemistry) & Binding domain. The author has an hindex of 1, co-authored 1 publications receiving 450 citations.
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The macro domain is an ADP-ribose binding module
Georgios I. Karras,Georg Kustatscher,Heeran R Buhecha,Mark D. Allen,Céline Pugieux,Fiona Sait,Mark Bycroft,Andreas G. Ladurner +7 more
TL;DR: In this article, the authors provide biochemical and structural evidence that macro domains are high affinity binding modules for ADP-ribose nucleotide nucleotides and reveal a conserved ligand binding pocket among the macro domain fold.