F
Florin Borcan
Researcher at West University of Timișoara
Publications - 90
Citations - 734
Florin Borcan is an academic researcher from West University of Timișoara. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 11, co-authored 81 publications receiving 552 citations. Previous affiliations of Florin Borcan include Yahoo!.
Papers
More filters
Journal ArticleDOI
The synergistic biologic activity of oleanolic and ursolic acids in complex with hydroxypropyl-γ-cyclodextrin.
Codruţa Şoica,Camelia Oprean,Florin Borcan,Corina Danciu,Cristina Trandafirescu,Dorina Coricovac,Zorin Crainiceanu,Cristina Dehelean,Melania Munteanu +8 more
TL;DR: An increased antitumor activity for the mixture of the two triterpenic acids, both single and in complex with cyclodextrin, is revealed, thus proving their complementary biologic activities.
Journal ArticleDOI
Betulinic Acid in Complex with a Gamma-Cyclodextrin Derivative Decreases Proliferation and in Vivo Tumor Development of Non-Metastatic and Metastatic B164A5 Cells
Codruta Soica,Corina Danciu,Germaine Savoiu-Balint,Florin Borcan,Rita Ambrus,István Zupkó,Florina Bojin,Dorina Coricovac,Sorina Ciurlea,Stefana Avram,Cristina Dehelean,Teodora Olariu,Petru Matusz +12 more
TL;DR: The study revealed the beneficial influence of betulinic acid inclusion into the cyclodextrin in terms of antiproliferative activity and in vivo tumor development.
Journal ArticleDOI
Genistein in 1:1 Inclusion Complexes with Ramified Cyclodextrins: Theoretical, Physicochemical and Biological Evaluation
Corina Danciu,Codruţa Şoica,Mircea Oltean,Stefana Avram,Florin Borcan,Erzsébet Csányi,Rita Ambrus,István Zupkó,Delia Muntean,Cristina Dehelean,Marius Craina,Ramona Amina Popovici +11 more
TL;DR: Theoretical data showed antiproliferative activity with different IC50 values for all tested cell lines, remarkable antimicrobial activity on Bacillus subtilis and antiangiogenic activity as revealed by CAM assay, a proof that the three CDs can be used for furtherer research towards practical use in the pharmaceutical and medical field.
Journal ArticleDOI
Evaluation and differentiation of the Betulaceae birch bark species and their bioactive triterpene content using analytical FT-vibrational spectroscopy and GC-MS.
TL;DR: This study shows that principal components of the birch tree extract can be rapidly recognized and differentiated based on their vibrational fingerprint band shape and intensity.
Journal ArticleDOI
Effect of the isoflavone genistein on tumor size, metastasis potential and melanization in a B16 mouse model of murine melanoma.
TL;DR: Genistein showed beneficial effects regarding tumor size, metastasis potential and melanization in a B16 mouse model of murine melanoma, and decreased the tumor volume and weight by approximately 30%.