Francesca Broggi

TL;DR: The results indicated dose-dependent cytotoxicity, genotoxicity and morphological transforming activity of cobalt nanoparticles and cobalt ions in Balb/3T3 cells indicated higher for Co-nano than for Co(2) after 2 and 24 h of exposure, while dose-effect relationships were overlapping after 72 h.

TL;DR: Force–displacement curves measured in indentation experiments performed with silicon nitride AFM probes with pyramidal tips on live cells agree well with the theoretical prediction and are used to determine the cell elasticity modulus and indenter-cell work of adhesion.

TL;DR: It is demonstrated that although aSiO(2)NPs are internalized in vitro by Balb/3T3 mouse fibroblasts, they do not trigger any cytotoxic or genotoxic effect and do not induce morphological transformation, suggesting that they might be a useful component in industrial applications.

TL;DR: The results suggest similar behavior of cytotoxicity induced by tested chemicals assessed by the three tests compared even if CFE remains the more sensitive, and the impedance-based on-line measuring 96-well plate method is the less laborious and easier test.

TL;DR: In this article, a complete physicochemical characterization of multi-wall carbon nanotubes (mwCNTs) in order to assess their potential toxicological effects in in vitro cell models using Colony Forming Efficiency (CFE) assay is presented.