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Francesco Costa

Researcher at University of Pisa

Publications -  78
Citations -  3869

Francesco Costa is an academic researcher from University of Pisa. The author has contributed to research in topics: Asthma & Irritable bowel syndrome. The author has an hindex of 27, co-authored 78 publications receiving 3445 citations.

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Calprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn’s disease

TL;DR: Faecal calprotectin proved to be an even stronger predictor of clinical relapse in UC than in CD, which makes the test a promising non-invasive tool for monitoring and optimising therapy.
Journal Article

T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease.

TL;DR: Results provide evidence for Hp-specific Th1 effectors in the gastric antrum of Hp -infected patients, where they may play a role in the genesis of either peptic ulcer or HP-associated gastric B cell lymphoma.
Journal ArticleDOI

Role of faecal calprotectin as non-invasive marker of intestinal inflammation.

TL;DR: Faecal calprotectin appears to be a promising and non-invasive biomarker of intestinal inflammation and may provide a useful test for the diagnosis and follow up of inflammatory bowel diseases.
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Different cytokine profile and antigen-specificity repertoire in Helicobacter pylori-specific T cell clones from the antrum of chronic gastritis patients with or without peptic ulcer.

TL;DR: Evidence is provided that the type of T helper cell response against Hp may vary according to the antigen involved and suggest that a polarized Th1 response may play a role in the genesis of peptic ulcer, whereas a local Th0 response may represent an individual host factor which contributes to lower the degree of gastric inflammation and prevent ulcer complication.