Francesco Izzo

TL;DR: The aims of this study were to verify the value of known prognostic factors and to devise a prognostic index more sensitive than the commonly used Okuda stage, and to produce a new prognostic system that accounts for both liver function and tumor characteristics.

TL;DR: RFA is a safe, well-tolerated, and effective treatment to achieve tumor destruction in patients with unresectable hepatic malignancies and multimodality treatment approaches that include RFA should be investigated.

TL;DR: In patients with cirrhosis and HCC, RFA produces effective local control of disease in a significant proportion of patients and can be performed safely with minimal complications.

TL;DR: This analysis provides robust evidence of the survival achieved with radioembolization, including those with advanced disease and few treatment options, and the most significant independent prognostic factors for survival upon multivariate analysis were ECOG status, tumor burden, international normalized ratio >1.2, and extrahepatic disease.