F
Francesco Squadrito
Researcher at University of Messina
Publications - 12
Citations - 2020
Francesco Squadrito is an academic researcher from University of Messina. The author has contributed to research in topics: Oxidative stress & Inflammasome. The author has an hindex of 6, co-authored 12 publications receiving 865 citations.
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Journal ArticleDOI
Oxidative Stress: Harms and Benefits for Human Health
Gabriele Pizzino,Natasha Irrera,Mariapaola Cucinotta,Giovanni Pallio,Federica Mannino,Vincenzo Arcoraci,Francesco Squadrito,Domenica Altavilla,Alessandra Bitto +8 more
TL;DR: In this review, the most recent findings in the oxidative stress field are described, highlighting both its bad and good sides for human health.
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The Role of NLRP3 Inflammasome in the Pathogenesis of Traumatic Brain Injury.
Natasha Irrera,Massimo Russo,Giovanni Pallio,Alessandra Bitto,Federica Mannino,Letteria Minutoli,Domenica Altavilla,Francesco Squadrito +7 more
TL;DR: The role of NLRP3 is pointed out in TBI and the hypothesis thatNLRP3 may be considered as a potential therapeutic target for the management of neuroinflammation in TBO is highlighted.
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Cadmium-Induced Oxidative Stress Impairs Glycemic Control in Adolescents.
Gabriele Pizzino,Natasha Irrera,Alessandra Bitto,Giovanni Pallio,Federica Mannino,Vincenzo Arcoraci,Federica Aliquò,Letteria Minutoli,Chiara De Ponte,Paola D’Andrea,Francesco Squadrito,Domenica Altavilla +11 more
TL;DR: Cd levels were significantly higher in adolescents living in the polluted area than in control age-matched subjects and oxidative stress plays a key role in cadmium-induced insulin resistance, increasing the risk of developing metabolic disorders.
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Protective Effects of Myo-Inositol and Selenium on Cadmium-Induced Thyroid Toxicity in Mice
Salvatore Benvenga,Herbert Marini,Antonio Micali,Jose Freni,Giovanni Pallio,Natasha Irrera,Francesco Squadrito,Domenica Altavilla,Alessandro Antonelli,Silvia Martina Ferrari,Poupak Fallahi,Domenico Puzzolo,Letteria Minutoli +12 more
TL;DR: MI, particularly in association with Se, defends mice from Cd-induced damage and the efficacy of this combination was greater than that of resveratrol, at least when using the follicular structure as a read-out for a comparison.
Journal ArticleDOI
Flavocoxid, a Natural Antioxidant, Protects Mouse Kidney from Cadmium-Induced Toxicity
Antonio Micali,Giovanni Pallio,Natasha Irrera,Herbert Marini,Vincenzo Trichilo,Domenico Puzzolo,Antonina Pisani,Consuelo Malta,Giuseppe Santoro,R. Laurà,Domenico Santoro,Francesco Squadrito,Domenica Altavilla,Antonino Germanà,Letteria Minutoli +14 more
TL;DR: A protective role of flavocoxid against Cd-induced oxidative damages in mouse kidney was demonstrated for the first time and may have a promising antioxidant role against environmental Cd harmful effects on glomerular and tubular lesions.