Francis Herodin

TL;DR: It is proposed that SDF-1 may contribute to hematopoiesis homeostasis by participating in the autonomous survival and cycling of progenitors under physiologic conditions and by protecting them from cell aggression in stress situations.

TL;DR: The present data suggest that, in nonhuman primates submitted to coronary artery ligation, mobilization by hematopoietic growth factors could promote angiogenesis in the infarcted myocardium, without detectable myocardial repair.

TL;DR: The results show that short- and long-term survival after irradiation depends on appropriate multiple cytokine combinations and at optimal concentrations, and it is proposed that an emergency cytokine regimen could be applied to nuclear accident victims as part of longer cytokine treatment, cell therapy, or both.

TL;DR: Administration of antiapoptotic cytokine combinations such as stem cell factor, Flt-3 ligand, thrombopoietin, and interleukin-3 (4F), may be important for multilineage recovery, particularly when these factors are administered early.

TL;DR: A new minipig model of severe CRS is developed that is close to human and allows development of stem cell therapy strategies that can be applied in treatment of human radiation burns.