F
François Alesch
Researcher at Medical University of Vienna
Publications - 58
Citations - 2329
François Alesch is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Deep brain stimulation & Subthalamic nucleus. The author has an hindex of 24, co-authored 55 publications receiving 2216 citations. Previous affiliations of François Alesch include University of Vienna.
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Journal ArticleDOI
No tissue damage by chronic deep brain stimulation in Parkinson's disease.
Christine Haberler,François Alesch,Peter R. Mazal,Peter Pilz,Kurt A. Jellinger,Michaela M. Pinter,Johannes A. Hainfellner,Herbert Budka +7 more
TL;DR: It is concluded that chronic DBS does not cause damage to adjacent brain tissue and all brains showed well‐preserved neural parenchyma and only mild gliosis around the lead track compatible with reactive changes due to surgical placement of the electrode.
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A positron emission tomographic study of subthalamic nucleus stimulation in Parkinson disease: enhanced movement-related activity of motor-association cortex and decreased motor cortex resting activity.
Andres O. Ceballos-Baumann,Henning Boecker,Peter Bartenstein,Isabella von Falkenhayn,Herrmann Riescher,Bastian Conrad,Jean R. Moringlane,François Alesch +7 more
TL;DR: Stimulation of the STN reduces the movement-related impairment of frontal motor association areas and the inappropriate motor cortex resting activity in Parkinson disease.
Journal ArticleDOI
Treatment of severe tardive dystonia with pallidal deep brain stimulation.
Thomas Trottenberg,Jens Volkmann,Günther Deuschl,Andrea A. Kühn,G.-H. Schneider,Jan-Uwe Müller,François Alesch,A. Kupsch +7 more
TL;DR: In five patients with medically refractory tardive dystonia, continuous bilateral high-frequency stimulation of the globus pallidus internus was associated with a rapid and substantial improvement of dySTONia and functional disability without adverse events.
Journal ArticleDOI
Stimulation of the ventral intermediate thalamic nucleus in tremor dominated Parkinson's disease and essential tremor
TL;DR: Vim neurostimulation is regarded as an effective and safe alternative to conventional thalamotomy and recommend that it should be considered in cases in which drag therapy has failed to affect Parkinsonian or essential tremor.
Journal ArticleDOI
Multiple-source current steering in subthalamic nucleus deep brain stimulation for Parkinson's disease (the VANTAGE study): a non-randomised, prospective, multicentre, open-label study
Lars Timmermann,Roshini Jain,Lilly Chen,Mohamed Maarouf,Michael T. Barbe,Niels Allert,Thomas Brucke,Iris Kaiser,Sebastian Beirer,Fernando Sejio,Esther Suarez,Beatriz Lozano,Claire Haegelen,Marc Vérin,Mauro Porta,Domenico Servello,Steven Gill,Alan L Whone,Nic Van Dyck,François Alesch +19 more
TL;DR: The VANTAGE study as mentioned in this paper showed that high-frequency deep brain stimulation (DBS) with a single electrical source is effective for motor symptom relief in patients with Parkinson's disease.