F
François Lemaire
Researcher at French Institute of Health and Medical Research
Publications - 168
Citations - 18093
François Lemaire is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Intensive care & Mechanical ventilation. The author has an hindex of 58, co-authored 168 publications receiving 17427 citations.
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Journal ArticleDOI
Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease.
Laurent Brochard,Jordi Mancebo,Marc Wysocki,Frédéric Lofaso,Giorgio Conti,Alain Rauss,Gérald Simonneau,Salvador Benito,A. Gasparetto,François Lemaire +9 more
TL;DR: In selected patients with acute exacerbations of chronic obstructive pulmonary disease, noninvasive ventilation can reduce the need for endotracheal intubation, the length of the hospital stay, and the in-hospital mortality rate.
Journal ArticleDOI
Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation
Laurent Brochard,A Rauss,Salvador Benito,Giorgio Conti,Jordi Mancebo,N Rekik,A. Gasparetto,François Lemaire +7 more
TL;DR: A randomized trial in three intensive care units in mechanically ventilated patients who met standard weaning criteria found a lower number of failures was found with PSV than with the other two modes, with the difference just reaching the level of significance.
Journal ArticleDOI
Tidal Volume Reduction for Prevention of Ventilator-induced Lung Injury in Acute Respiratory Distress Syndrome
Laurent Brochard,Françoise Roudot-Thoraval,Eric Roupie,Christophe Delclaux,Jean Chastre,Enrique Fernández-Mondéjar,Clémenti E,Jordi Mancebo,Dimitros Matamis,Marco Ranieri,Lluis Blanch,Rodi G,H Mentec,Didier Dreyfuss,Miquel Ferrer,Christian Brun-Buisson,Martin J. Tobin,François Lemaire +17 more
TL;DR: It is concluded that no benefit could be observed with reduced VT titrated to reach plateau pressures around 25 cm H2O compared with a more conventional approach in which normocapnia was achieved with plateau pressures already below 35 cm H 2O.
Journal ArticleDOI
Symptoms of anxiety and depression in family members of intensive care unit patients: Ethical hypothesis regarding decision-making capacity
Frédéric Pochard,Elie Azoulay,Sylvie Chevret,François Lemaire,Philippe Hubert,P Canoui,Marc Grassin,Robert Zittoun,J R Le Gall,Jean-François Dhainaut,Benoit Schlemmer +10 more
TL;DR: Characterization of symptoms that reflect anxiety and depression in family members visiting intensive care patients should be of major relevance to the ethics of involving family members in decision-making, particularly about end-of-life issues.
Journal ArticleDOI
Reversal of acute exacerbations of chronic obstructive lung disease by inspiratory assistance with a face mask.
Laurent Brochard,Daniel Isabey,Jacques Piquet,Piedade Amaro,J. Mancebo,Amen-Allah Messadi,Christian Brun-Buisson,Alain Rauss,François Lemaire,Alain Harf +9 more
TL;DR: Inspiratory positive airway pressure delivered by a face mask can obviate the need for conventional mechanical ventilation in patients with acute exacerbations of chronic obstructive pulmonary disease.