F
Frank A. Lederle
Researcher at Veterans Health Administration
Publications - 128
Citations - 12486
Frank A. Lederle is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: Abdominal aortic aneurysm & Aortic aneurysm. The author has an hindex of 48, co-authored 128 publications receiving 11358 citations. Previous affiliations of Frank A. Lederle include University of Minnesota & Edward Hines, Jr. VA Hospital.
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Journal ArticleDOI
Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial
Frank A. Lederle,Julie A. Freischlag,Tassos C. Kyriakides,Frank T. Padberg,Jon S. Matsumura,Ted R. Kohler,Peter H. Lin,Jessie M. Jean-Claude,Dolores F. Cikrit,Kathleen M. Swanson,Peter Peduzzi +10 more
TL;DR: Perioperative mortality was low for both procedures and lower for endovascular than open repair in this report of short-term outcomes after elective AAA repair, and the early advantage of endov vascular repair was not offset by increased morbidity or mortality in the first 2 years after repair.
Journal ArticleDOI
Immediate repair compared with surveillance of small abdominal aortic aneurysms.
Frank A. Lederle,Samuel E. Wilson,Gary R. Johnson,Donovan B. Reinke,Fred N. Littooy,Charles W. Acher,David J. Ballard,Louis M. Messina,Ian L. Gordon,Edmund P. Chute,William C. Krupski,Steven J. Busuttil,Gary W. Barone,Steven Sparks,Linda M. Graham,Joseph H. Rapp,Michel S. Makaroun,Gregory L. Moneta,Robert A. Cambria,Raymond G. Makhoul,Darwin Eton,Howard J. Ansel,Julie A. Freischlag,Dennis F. Bandyk +23 more
TL;DR: The rate of death from any cause, the primary outcome, was not significantly different in the two groups (relative risk in the immediate-repair group as compared with the surveillance group), and the rate of repair had been performed in 92.6 percent of the patients in the immediately- Repair group and 61.6% of those in the Surveillance group.
Journal ArticleDOI
Prevalence and Associations of Abdominal Aortic Aneurysm Detected through Screening
Frank A. Lederle,Gary R. Johnson,Samuel E. Wilson,Edmund P. Chute,Fred N. Littooy,Dennis F. Bandyk,William C. Krupski,Gary W. Barone,Charles W. Acher,David J. Ballard +9 more
TL;DR: The Aneurysm Detection and Management (ADAM) study is an ongoing randomized clinical trial comparing two strategies for the management of AAA in patients 50 to 79 years of age with asymptomatic AAAs.
Journal ArticleDOI
Long-term mortality after screening for colorectal cancer.
Aasma Shaukat,Steven J. Mongin,Mindy S. Geisser,Frank A. Lederle,John H. Bond,Jack S. Mandel,Timothy R. Church +6 more
TL;DR: The effect of screening with fecal occult-blood testing on colorectal-cancer mortality persists after 30 years but does not influence all-cause mortality, which supports the effect of polypectomy.
Journal ArticleDOI
The Aneurysm Detection and Management Study Screening Program Validation Cohort and Final Results
Frank A. Lederle,Gary R. Johnson,Samuel E. Wilson,Edmund P. Chute,Robert J. Hye,Michel S. Makaroun,Gary W. Barone,Dennis F. Bandyk,Gregory L. Moneta,Raymond G. Makhoul +9 more
TL;DR: Age, smoking, family history of AAA, and atherosclerotic diseases remained the principal positive associations with AAAs, and female sex, diabetes, and black race remained the Principal negative associations.