F
Frank J. Dixon
Researcher at Scripps Research Institute
Publications - 7
Citations - 2382
Frank J. Dixon is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Immunoglobulin G & Antibody. The author has an hindex of 5, co-authored 7 publications receiving 2374 citations.
Papers
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Journal ArticleDOI
A method of trace iodination of proteins for immunologic studies.
Journal ArticleDOI
Serum transfer of collagen-induced arthritis in mice.
John M. Stuart,Frank J. Dixon +1 more
TL;DR: Although susceptibility to arthritis from immunization is H-2 linked, these studies clearly demonstrate that passive transfer of arthritis depends upon injection of specific antibody and not on other host factors.
Journal ArticleDOI
The hu-PBL-SCID mouse model. Long-term human serologic evolution associated with the xenogeneic transfer of human peripheral blood leukocytes into SCID mice.
TL;DR: The majority of hu-PBL-SCID mouse sera analyzed by high resolution electrophoresis had a smear appearance suggestive of diverse human Ig, generally with superimposed multiple faint mIg, associated with lymphoproliferative diseases.
Journal ArticleDOI
In vivo immunosuppression by targeting a novel protease receptor
Michel A. Duchosal,Annette L. Rothermel,Patricia J. McConahey,Frank J. Dixon,Dario C. Altieri +4 more
TL;DR: In vivo administration of mAb 2E1 to severe-combined-immunodeficient mice injected with human peripheral blood leukocytes suppressed production of human immunoglobulin, abolished graft-versus-host disease, and protected these xenochimaeric mice from Epstein–Barr-virus-induced human lymphoproliferative disease.
Patent
Method for producing human antibodies in a non-human animal, and animals therefor
TL;DR: In this article, the authors describe methods for producing a non-human animal having a reconstituted human immune system useful for producing human antibodies, such as an immunodeficient mouse.