Showing papers by "Frank Jülicher published in 1998"
TL;DR: A discontinuity in the velocity force relationship suggests the existence of dynamical phase transition and PMMA (poly(methylmethacrylate)) gratings, which act as rails for actin, allow one for the first time to explore three quadrants of the force velocity diagram.
Abstract: We have developed a novel technique which allows one to direct the two dimensional motion of actin filaments on a myosin coated sheet using a weak electric field parallel to the plane of motion. The filament velocity can be increased or decreased, and even reversed, as a function of orientation and strength of the field. PMMA (poly(methylmethacrylate)) gratings, which act as rails for actin, allow one for the first time to explore three quadrants of the force velocity diagram. We discuss effective friction, duty ratio and stall force at different myosin densities. A discontinuity in the velocity force relationship suggests the existence of dynamical phase transition.
149 citations
TL;DR: The model can simulate optical trap experiments and allows us to study the dynamics of chemically halted complexes that are important for footprinting studies and finds that the effective stall force is a sequence-dependent, statistical quantity, whose distribution depends on the observation time.
74 citations
32 citations