F
Frank R. Burden
Researcher at Commonwealth Scientific and Industrial Research Organisation
Publications - 67
Citations - 3796
Frank R. Burden is an academic researcher from Commonwealth Scientific and Industrial Research Organisation. The author has contributed to research in topics: Artificial neural network & Quantitative structure–activity relationship. The author has an hindex of 30, co-authored 67 publications receiving 3352 citations. Previous affiliations of Frank R. Burden include Flinders University & Monash University.
Papers
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Journal ArticleDOI
Comparison of Linear and Nonlinear Classification Algorithms for the Prediction of Drug and Chemical Metabolism by Human UDP‐Glucuronosyltransferase Isoforms.
Michael J. Sorich,John O. Miners,Ross A. McKinnon,David A. Winkler,Frank R. Burden,Paul A. Smith +5 more
TL;DR: In this paper, the authors compared the performance of different SVM-based methods to classify substrates and nonsubstrates of 12 isoforms of human UDP-glucuronosyltransferase (UGT), an enzyme involved in the metabolism of drugs, nondrug xenobiotics, and endogenous compounds.
Book ChapterDOI
The Computer Simulation of High Throughput Screening of Bioactive Molecules
Frank R. Burden,David A. Winkler +1 more
TL;DR: The data sets which derive from combinatorial chemistry and high throughput screening are often so massive that QSAR is the method of choice, and it has been successfully applied to many drug and agrochemical design problems.
Journal ArticleDOI
The potential function of ArHF
Frank R. Burden,A. Cuno +1 more
TL;DR: In this article, the vibration-rotation spectrum of ArHF has been analyzed to produce a potential function, by using the exact Hamiltonian and numerical wavefunctions, and the potential function has been applied to the ArHF signal.
Journal ArticleDOI
Quadrupol-hyperfeinstruktur im mikrowellenspektrum von pyrazol
Journal ArticleDOI
Triatomic molecules: meeting places for experiment and theory
TL;DR: In this article, the use of alternative functions for expressing the potential energy of a triatomic molecule in internal coordinates is proposed, and the energy of H 2 O is described using these functions.