F
Fraser McDonald
Researcher at King's College London
Publications - 140
Citations - 5968
Fraser McDonald is an academic researcher from King's College London. The author has contributed to research in topics: Molar & Orthognathic surgery. The author has an hindex of 34, co-authored 139 publications receiving 5522 citations. Previous affiliations of Fraser McDonald include Guy's Hospital & King's College.
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Physical and chemical properties of a new root-end filling material.
TL;DR: MTA has a pH of 10.2 initially, which rises to 12.5 three hours after mixing, and is more radiopaque than Super-EBA and IRM, and none of the materials tested showed any solubility under the conditions of this study.
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Cellular response to Mineral Trioxide Aggregate
TL;DR: It seems that MTA offers a biologically active substrate for bone cells and stimulates IL production and stimulates macrophage colony-stimulating factor.
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Mineral trioxide aggregate stimulates a biological response in human osteoblasts
TL;DR: A novel material is reported that appears to stimulate cytokine production in human osteoblasts and allow good adherence of the cells to the material and alkaline phosphatase activity.
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Osteoblast biocompatibility of mineral trioxide aggregate.
TL;DR: It appears that the variants of MTA are biocompatible and suitable for use in clinical trials, as good cell growth on MTA was shown and production of M-CSF was high for all materials.
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An evaluation of accelerated Portland cement as a restorative material.
TL;DR: Evidence is provided that both APC variants are non-toxic and may have potential to promote bone healing and further development of APC is indicated to produce a viable dental restorative material and possibly a material for orthopaedic treatment.