Fredric B. Kraemer

TL;DR: An update is provided on the role of LD-associated proteins and LDs in metabolic disease and the regulation of LD physiology and metabolism influence the risk of developing metabolic diseases such as diabetes.

TL;DR: Accumulating evidence has defined important functions for HSL in normal physiology, affecting adipocyte lipolysis, steroidogenesis, spermatogenesis, and perhaps insulin secretion and insulin action; however, direct links between abnormal expression or genetic variations of HSL and human disorders, such as obesity, insulin resistance, type 2 diabetes, and hyperlipidemia, await further clarification.

TL;DR: The results indicated that estimates of insulin resistance generated by the two methods were highly correlated and indicated that the greater the degree of glucose intolerance, the more severe the insulin resistance.

TL;DR: Activation of the ERK pathway appears to be able to regulate adipocyte lipolysis by phosphorylating HSL on Ser600 and increasing the activity of HSL.

TL;DR: It is concluded that there is a close association between a high level of plasma inactive renin and the presence of microvascular complications, and that the level of active renin can be modified by intensive treatment of diabetes.