F
Frits Mastik
Researcher at Erasmus University Rotterdam
Publications - 156
Citations - 6390
Frits Mastik is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Intravascular ultrasound & Vulnerable plaque. The author has an hindex of 39, co-authored 155 publications receiving 5932 citations. Previous affiliations of Frits Mastik include Erasmus University Medical Center & Utrecht University.
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Journal ArticleDOI
Arterial wall characteristics determined by intravascular ultrasound imaging: An in vitro study☆
Elma J. Gussenhoven,C. E. Essed,Charles T. Lancée,Frits Mastik,Peter A.V. Frietman,Frans C. van Egmond,J.H.C. Reiber,Hans Bosch,Hero van Urk,Jos R.T.C. Roelandt,Nicolaas Bom +10 more
TL;DR: This study indicates that characterization of the type of artery and detection of arterial wall disease are possible with use of an intravascular ultrasound imaging technique.
Journal ArticleDOI
Effects of the Direct Lipoprotein-Associated Phospholipase A 2 Inhibitor Darapladib on Human Coronary Atherosclerotic Plaque
Patrick W. Serruys,Hector M. Garcia-Garcia,Paweł Buszman,Paul Erne,Stefan Verheye,Michael Aschermann,Henrikus Duckers,Øyvind Bleie,Dariusz Dudek,Hans Erik Bøtker,Clemens von Birgelen,Don D'Amico,Tammy Hutchinson,Andrew Zambanini,Frits Mastik,Gerrit Anne van Es,Antonius F.W. van der Steen,D. Geoffrey Vince,Peter Ganz,Christian W. Hamm,William Wijns,Andrew Zalewski,Andrew Zalewski +22 more
TL;DR: Comparing the effects of 12 months of treatment with darapladib or placebo on coronary atheroma deformability and plasma high-sensitivity C-reactive protein in 330 patients with angiographically documented coronary disease suggests that Lp-PLA2 inhibition may represent a novel therapeutic approach.
Journal ArticleDOI
Characterizing Vulnerable Plaque Features With Intravascular Elastography
Johannes A. Schaar,Chris L. de Korte,Frits Mastik,Chaylendra Strijder,Gerard Pasterkamp,Eric Boersma,Patrick W. Serruys,Anton F. W. van der Steen +7 more
TL;DR: Intravascular elastography has a high sensitivity and specificity to detect vulnerable plaques in vitro, and can differentiate between different plaques phenotypes.
Journal ArticleDOI
Contactless multiple wavelength photoplethysmographic imaging: a first step toward "SpO2 camera" technology.
TL;DR: A route toward contactless imaging of arterial oxygen saturation (SpO2) distribution within tissue is described, based upon detection of a two-dimensional matrix of spatially resolved optical plethysmographic signals at different wavelengths, which shows potential for non-contact 2-D imaging reflection-mode pulse oximetry.
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Identification of Atherosclerotic Plaque Components With Intravascular Ultrasound Elastography In Vivo A Yucatan Pig Study
Chris L. de Korte,Marion J. Sierevogel,Frits Mastik,Chaylendra Strijder,Johannes A. Schaar,Evelyn Velema,Gerard Pasterkamp,P. W. Serruys,Anton F. W. van der Steen +8 more
TL;DR: This is the first time that intravascular ultrasound elastography has been validated in vivo to identify fatty plaques, and high-strain spots are associated with the presence of macrophages.