Furn F. Knapp

TL;DR: It is concluded that CD36 facilitates a large fraction of fatty acid uptake by heart, skeletal muscle, and adipose tissues and thatCD36 deficiency in humans is the cause of the reported defect in myocardial BMIPP uptake.

TL;DR: A broad understanding and discussion of the issues associated with 177Lu production and processing approaches would not only ensure sustained growth and future expansion for the availability and use of 177Lu-labeled radiopharmaceuticals, but also help future developments.

TL;DR: In this paper, the authors determined whether loss of CD36 function in FA uptake is a primary determinant of the spontaneously hypertensive rat (SHR) phenotype and showed that supplementing the diet with short-chain fatty acids, which do not require CD36-facilitated transport, eliminated the increase in glucose uptake, the hyperinsulinemia, and the heart hypertrophy in the SHR.

TL;DR: It is suggested that the prolonged myocardial retention observed with DMIPP in vivo may result from inhibition of β oxidation, and [123I]DMIPP should be useful for evaluation of aberrations in regionalMyocardial uptake.