Futoshi Izumi

TL;DR: Results indicate that cultured bovine adrenal medulla cells have at least three distinct ion channels: nicotinic acetylcholine receptor-associated Na channels which are not inhibited by tetrodotoxin, voltage-dependent Na channelsWhich are kept activated by veratridine and inhibited by Tetrodtoxin and (3) voltage- dependent Ca channels.

TL;DR: It is suggested that staurosporine inhibits CaM kinase II by interacting with the catalytic domain, distinct from the ATP‐binding site or substrate‐ binding site, of the enzyme and that Staurospora is an effective inhibitor for CaM Kinase II in the cell system.

TL;DR: The results suggest that multiple P2x receptors, including P2X3, are functionally expressed in SON neurones, and that activation of these receptors induces cationic currents and Ca2+ entry.

TL;DR: It is concluded that ATP increases DNA synthesis and enhances the proliferative effects of growth factors through P2X receptors by activating a mitogen-activated protein kinase pathway.

TL;DR: Signaling of the cannabinoid CB1 and CB2 receptors through phospholipase C and G protein-coupled inwardly rectifying K+ channels (GIRK) was studied after their expression in COS7 cells and Xenopus oocytes to suggest two new signaling pathways for the cannabinoid receptors.