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G. Esposito

Researcher at National Institutes of Health

Publications -  30
Citations -  3032

G. Esposito is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Working memory & Prefrontal cortex. The author has an hindex of 16, co-authored 29 publications receiving 2910 citations. Previous affiliations of G. Esposito include University of Southern California.

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Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia.

TL;DR: The tight within-patient coupling of these values, with decreased PFC activation predicting exaggerated striatal 6-fluorodopa uptake, supports the hypothesis that prefrontal cortex dysfunction may lead to dopaminergic transmission abnormalities.
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Modulation of cognition-specific cortical activity by gonadal steroids: A positron-emission tomography study in women

TL;DR: Data from H215O positron-emission tomography demonstrate that the hormonal milieu modulates cognition-related neural activity in humans during three pharmacologically controlled hormonal conditions spanning 4-5 months.
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H215O PET validation of steady‐state arterial spin tagging cerebral blood flow measurements in humans

TL;DR: The work presented here compared CBF values measured using steady‐state arterial spin tagging with CBFvalues measured in the same group of human subjects using the H215O IV bolus PET method.
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A comparison of rCBF patterns during letter and semantic fluency.

TL;DR: In this paper, the functional neuroanatomies underlying letter and category fluency were evaluated with oxygen-15 water regional cerebral blood flow positron emission tomography (PET) in 18 normal controls.
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Context-dependent, neural system-specific neurophysiological concomitants of ageing: mapping PET correlates during cognitive activation.

TL;DR: Results indicate that, despite some cognitive overlap between the two tasks and the age-related cognitive decline in both, many of the changes in rCBF activation with age were task-specific, reflecting functional alteration of the different neural circuits normally engaged by young subjects during the WCST and RPM.