G
G. Ixart
Researcher at University of Montpellier
Publications - 39
Citations - 2015
G. Ixart is an academic researcher from University of Montpellier. The author has contributed to research in topics: Circadian rhythm & Hypothalamus. The author has an hindex of 24, co-authored 39 publications receiving 1938 citations. Previous affiliations of G. Ixart include French Institute of Health and Medical Research.
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Journal ArticleDOI
Effects of lesions of the suprachiasmatic nuclei and of p-chlorophenylalanine on the circadian rhythms of adrenocorticotrophic hormone and corticosterone in the plasma, and on locomotor activity of rats.
TL;DR: The proposition that both the suprachiasmatic nuclei and the serotoninergic system play an irreplaceable role in the mechanism of ACTH secretory rhythms is supported.
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A single brain-derived neurotrophic factor injection modifies hypothalamo-pituitary-adrenocortical axis activity in adult male rats.
TL;DR: The results strongly suggest that BDNF could be a stress-responsive intercellular messenger since when it is exogenously administered acts as an important and early component in the activation and recruitment of hypothalamic CRH and AVP neurons.
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Brain-derived neurotrophic factor and hypothalamic-pituitary-adrenal axis adaptation processes in a depressive-like state induced by chronic restraint stress.
Gaëlle Naert,G. Ixart,G. Ixart,Tangui Maurice,Tangui Maurice,Lucia Tapia-Arancibia,Lucia Tapia-Arancibia,Laurent Givalois,Laurent Givalois +8 more
TL;DR: It was shown that chronic restraint stress induced a depressive-like state that was sustained by mechanisms associated with BDNF regulation and the HPA axis response to novel acute stress was modified, suggesting adaptive mechanisms.
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Time-Course and Regional Analyses of the Physiopathological Changes Induced after Cerebral Injection of an Amyloid β Fragment in Rats
Charleine Zussy,Anthony Brureau,Brice Delair,Stéphane Marchal,Emeline Keller,G. Ixart,Gaëlle Naert,Johann Meunier,Nathalie Chevallier,Tangui Maurice,Laurent Givalois +10 more
TL;DR: The acute intracerebroventricular Aβ(25-35) injection induced substantial central modifications in rats, highly reminiscent of the human physiopathology, that could contribute to physiological and cognitive deficits observed in AD.
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Diurnal-stimulated and stress-induced ACTH release in rats is mediated by ventral noradrenergic bundle
TL;DR: Female rats were bilaterally injected with 3 micrograms of 6-hydroxydopamine dissolved in 0.2 microliter saline, via a glass micropipet stereotaxically implanted into the ventral noradrenergic-ascending bundle (VNAB), leading to pharmacological destruction of the VNAB and a striking decrease in the histofluorescence of hypothalamic catecholaminergic innervation.