G. Sokal

TL;DR: Five patients, four women and one man, age 32-8- yr, all whites, had refractory anemia with the same abnormal bone marrow karyotype, i.e., a partial deletion of the long arm of the No. 5 chromosome, which constitutes another example of the association between a specific abnormal chromosome and a distinct hematologic disorder.

TL;DR: It appears that in certain human hemopathies, e.g., chronic myelocytic leukemia and BL, the deletion of a specific chromosome, nos. 22 and 8, respectively, may be the key karyotypic event associated with the disease, rather than the site of translocation of the deleted segments.