G. Vaughan Hudson

TL;DR: An initial policy of watchful waiting in patients with asymptomatic, advanced stage low-grade non-Hodgkin lymphoma is appropriate, especially in patients older than age 70 years.

TL;DR: In Working Formulation F, G, and H NHL of B-cell type, expression of Bcl-2 protein predicted independently for relapse, and major breakpoint region (MBR) status had no significant influence on any of the outcome measures.

TL;DR: A multivariate analysis of factors influencing prognosis in clinical stages I and IIA disease shows that laparotomy has no significant effect but that age, sex, erythrocyte sedimentation (ESR), the presence or absence of mediastinal involvement and, especially, pathological grade are the most important factors influencing overall survival.

TL;DR: Long-term results in young patients with clinical stage 1 disease are encouraging, and it will be difficult to demonstrate improved survival with initial chemotherapy either with or without radiotherapy, until new prognostic factors are found to identify poor-risk patients.

TL;DR: A retrospective analysis of patients with Non-Hodgkin's Lymphoma involving the gastrointestinal tract and entered into BNLI trials and studies between 1974-1988 found evidence of tumour origin from MALT as the only factor to attain prognostic significance in patients with gastric involvement.