Gabriel Nistor

TL;DR: It is demonstrated that human embryonic stem cells and human neural stem cells have the ability to differentiate into high purity neuronal progenitor or oligodendrocyte progenitors cultures in in vitro cultures.

TL;DR: Whereas distant migration was not encountered in the liver or lung, 2 transplanted rats developed abnormal foci of growth, that is, tumors, from the external anal sphincter—raising further safety questions.

TL;DR: In this article, the authors provided cancer stem cells, for use in stimulating immune response against a cancer, such as hepatocellular carcinoma (HCC), and methods for preparing and purifying the stem cells were provided.

TL;DR: In this paper, an immunopotent tumor-specific cancer cell product containing an immunogenic composition containing immunostimulatory amount of an isolated population of dendritic cells contacted ex vivo with a cancer- specific cancer stem cell derived from a tumor cell, a tumor cluster, tumor cell aggregate or a combination thereof expressing at least one cancer-specific antigen, the tumor cell or aggregate being derived from peripheral blood; and an adjuvant; and a pharmaceutically acceptable carrier.

TL;DR: A multicenter phase II trial was designed to determine: (1) the success rate of manufacturing the Aivita GBM vaccine (AV-GBM-1), (2) Adverse Events (AE) associated with AVGBM1 administration, and (3) survival as mentioned in this paper .