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Gabriel Nistor
Researcher at University of California, Irvine
Publications - 59
Citations - 3366
Gabriel Nistor is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Stem cell & Transplantation. The author has an hindex of 19, co-authored 52 publications receiving 3087 citations. Previous affiliations of Gabriel Nistor include University of California.
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Journal ArticleDOI
Reversal of deficits in aged skeletal muscle during disuse and recovery in response to treatment with a secrotome product derived from partially differentiated human pluripotent stem cells
Dennis K Fix,Ziad S. Mahmassani,Jonathan J Petrocelli,Naomi M de Hart,Patrick J Ferrara,Jessie S Painter,Gabriel Nistor,Thomas E. Lane,Hans S. Keirstead,Micah J. Drummond +9 more
TL;DR: In this paper, the authors examined the effectiveness of a uniquely developed secretome product (STEM) on aged skeletal muscle mass and function during disuse and recovery, and found that STEM-treated mice compared to PBS had greater soleus muscle mass, fiber cross-sectional area (CSA), and grip strength during CON and recovery experimental conditions and less muscle atrophy and weakness during HU.
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Genomic, proteomic, and immunologic associations with a durable complete remission of measurable metastatic melanoma induced by a patient-specific dendritic cell vaccine.
TL;DR: The data suggested that by 3 weeks after the first DCV injection, vaccine-induced changes in this particular patient were most consistent with enhanced innate and Th1 immune responses rather than Th2 or Th17.
Journal ArticleDOI
Preliminary observations on soluble programmed cell death protein-1 as a prognostic and predictive biomarker in patients with metastatic melanoma treated with patient-specific autologous vaccines.
Robert O. Dillman,Gabriel Nistor,Bryce T McLelland,Candace Hsieh,Aleksandra J. Poole,Andrew N. Cornforth,Hans S. Keirstead +6 more
TL;DR: Preliminary observations suggest that sPD-1 might be a useful biomarker for melanoma patients being considered for treatment with this DCV vaccine, and/or to predict efficacy after only three injections, but this would have to be confirmed in larger studies.
Journal Article
Human Stem Cell-Derived Skin Progenitors Produce Alpha 2-HS Glycoprotein (Fetuin): A Revolutionary Cosmetic Ingredient.
Gabriel Nistor,Aleksandra J. Poole,Zoe Diana Draelos,Mary P. Lupo,Thomas Tzikas,Jerome H Liu,Hans S. Keirstead +6 more
TL;DR: The hypothesis that cosmetic application of stem cell-derived skin lineage precursor secretions containing fetuin and growth factors beneficial for human skin development and maintenance, positively influence intrinsic and extrinsic aging is supported.
Journal ArticleDOI
Phase I trial of active specific immunotherapy with autologous dendritic cells pulsed with autologous irradiated tumor stem cells in hepatitis B positive patients with hepatocellular carcinoma
Michael Bayer,Xiaojin Wang,Chengwei Chen,Xiaosong Chen,Qingchun Fu,Jia He,William Wei Cao,Craig Fredrickson,Jessica Cannon,Andrew N. Cornforth,Gabriel Nistor,Robert O. Dillman +11 more
TL;DR: A Phase I safety trial in HCC patients with previously untreated HCC who were candidates for surgical resection, but not curable by resection or liver transplant was warranted, finding effective nontoxic adjunctive treatments might improve outcomes.