Gabriel O'Riordain

TL;DR: Cross-reactivity with Bet v 1 was proven by cross-inhibition experiments, which provides further support for the existence of the birch-celery syndrome and for the suggestion that allergies to some vegetable foods are epiphenomena to allergies caused by inhalation of tree pollen.

TL;DR: A thaumatin-like protein in cherry has been identified as a major allergen (Pru a 2) that should be checked for the capability to elicit an IgE-mediated allergic reaction.

TL;DR: It is reported here that Bet v 1 proteins indeed possess an intrinsic ribonucleolytic activity as they can digest different RNA substrates in vitro, but show no activity on single or double-stranded DNA.

TL;DR: In this paper, a mutation of the furin recognition site in prM resulted in the secretion of two distinct size classes of particles that could be separated by sucrose gradient centrifugation.

TL;DR: These double mutants were found to be highly attenuated and capable of inducing a protective immune response in mice at even lower inoculation doses than the previously characterized 16-amino-acid-residue deletion mutant, suggesting that the combination of large deletions and second-site mutations may be a superior way to generate safe, attenuated flavivirus vaccine strains.