G
Gabriella Gaudioso
Researcher at Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Publications - 28
Citations - 625
Gabriella Gaudioso is an academic researcher from Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 12, co-authored 24 publications receiving 405 citations. Previous affiliations of Gabriella Gaudioso include University of Milan.
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Journal ArticleDOI
MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.
Vittoria Poli,Luca Fagnocchi,Luca Fagnocchi,Alessandra Fasciani,Alessandro Cherubini,Stefania Mazzoleni,Sara Ferrillo,Annarita Miluzio,Gabriella Gaudioso,Gabriella Gaudioso,Valentina Vaira,Valentina Vaira,Alice Turdo,Miriam Gaggianesi,Aurora Chinnici,Elisa Lipari,Silvio Bicciato,Silvano Bosari,Silvano Bosari,Matilde Todaro,Alessio Zippo,Alessio Zippo +21 more
TL;DR: The authors show MYC-driven tumor initiation is reliant on cell reprogramming via an epigenetic program which leads to mammary luminal epithelial cells acquiring basal/stem cell-like properties, thus establishing a therapeutic rational for treating basal-like breast cancers.
Journal ArticleDOI
microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts
Valentina Vaira,Leda Roncoroni,Leda Roncoroni,Donatella Barisani,Gabriella Gaudioso,Silvano Bosari,Silvano Bosari,Gaetano Bulfamante,Luisa Doneda,Dario Conte,Carolina Tomba,Maria Teresa Bardella,Stefano Ferrero,Stefano Ferrero,Martina Locatelli,Luca Elli +15 more
TL;DR: The analysis of miRNAs deserves further consideration for its potential use in the treatment and management of CD.
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Mismatch Repair Protein Loss as a Prognostic and Predictive Biomarker in Breast Cancers Regardless of Microsatellite Instability.
Nicola Fusco,Gianluca Lopez,Chiara Corti,Chiara Pesenti,Chiara Pesenti,Patrizia Colapietro,Patrizia Colapietro,Giulia Ercoli,Gabriella Gaudioso,Alice Faversani,Donatella Gambini,Anna Michelotti,Luca Despini,Concetta Blundo,Valentina Vaira,Valentina Vaira,Monica Miozzo,Monica Miozzo,Stefano Ferrero,Silvano Bosari +19 more
TL;DR: IMR protein loss is a more common event than MSI and shows intra-tumor heterogeneity, and MMR IHC allows the identification of clinically relevant subclasses of breast cancer patients, provided that multiple areas of the tumor are analyzed.
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PTEN Alterations and Their Role in Cancer Management: Are We Making Headway on Precision Medicine?
Nicola Fusco,Nicola Fusco,Elham Sajjadi,Konstantinos Venetis,Konstantinos Venetis,Gabriella Gaudioso,Gianluca Lopez,Chiara Corti,Elena Guerini Rocco,Elena Guerini Rocco,Carmen Criscitiello,Umberto Malapelle,Marco Invernizzi +12 more
TL;DR: An update on the current state of knowledge on biologic and genetic alterations of PTEN across the most frequent solid tumors, as well as on their actual and/or possible clinical applications are provided.
Journal ArticleDOI
Intratumor Heterogeneity of ALK-Rearrangements and Homogeneity of EGFR-Mutations in Mixed Lung Adenocarcinoma.
Federica Zito Marino,Giuseppina Liguori,Gabriella Aquino,Elvira La Mantia,Silvano Bosari,Stefano Ferrero,Lorenzo Rosso,Gabriella Gaudioso,Nicla De Rosa,Marianna Scrima,Nicola Martucci,Antonello La Rocca,Nicola Normanno,Alessandro Morabito,Gaetano Rocco,Gerardo Botti,Renato Franco +16 more
TL;DR: The data suggests that EGFR-mutations is generally homogeneously expressed and ALK-rearrangement showed an intratumor heterogeneity in both mixed adenocarcinomas and adenosquamous carcinomas, which could lead to a possible impact on the therapeutic responses and the disease outcomes.