Gaetana Albanese

TL;DR: In this paper, a review of metformin's beneficial effects on endothelium-dependent vascular response in type 2 diabetes patients is presented, which could preempt development of atherosclerosis.

TL;DR: Correcting cardiorenal risk factors, metabolic adjustments ameliorating myocardial substrate utilization, and optimization of ventricular loading conditions through effects on diuresis, natriureis, and vascular function appear to be the main underlying mechanisms for the observed cardi Lorenal protection.

TL;DR: In this paper, the major pathophysiological changes and the underlying mechanisms leading to myocardial remodeling and cardiac functional derangement in DM-CMP were outlined. But, the authors did not consider the effect of other risk factors such as metabolic abnormalities such as lipotoxicity and glucotoxicity.

TL;DR: In this paper, a review aimed to analyze the cardiovascular protective mechanisms of SGLT2 inhibition in patients with Type 2 diabetes mellitus and their impact on endothelial function, which is a known independent risk factor for atherosclerotic cardiovascular disease.

TL;DR: A large proportion of rheumatologic patients can currently benefit from metformin, such as those with concomitant obesity and type 2 diabetes, two conditions strongly associated with r heumatoid arthritis, osteoarthritis, and gout, as well asThose with diabetes secondary to steroid therapy.