G
Gang Zeng
Researcher at University of California, Los Angeles
Publications - 51
Citations - 3788
Gang Zeng is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 25, co-authored 51 publications receiving 3586 citations. Previous affiliations of Gang Zeng include National Institutes of Health & Georgetown University Medical Center.
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Journal ArticleDOI
Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells.
Gang Zeng,Michael J. Quon +1 more
TL;DR: The data suggest that NO is a novel effector of insulin signaling pathways that are also involved with glucose metabolism, and that PI 3-kinase activity is required for insulin-stimulated glucose transport.
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Prostaglandin E2 Induces FOXP3 Gene Expression and T Regulatory Cell Function in Human CD4+ T Cells
Felicita Baratelli,Ying Lin,Li Zhu,Seok-Chul Yang,Nathalie Heuzé-Vourc'h,Gang Zeng,Karen L. Reckamp,Mariam Dohadwala,Sherven Sharma,Steven M. Dubinett +9 more
TL;DR: PGE2 enhances the in vitro inhibitory function of human purified CD4+CD25+ T reg cells and induces a regulatory phenotype in CD4-CD25− T cells, the first report indicating that PGE2 can modulate FOXP3 expression and T reg function in human lymphocytes.
Journal Article
A Breast and Melanoma-Shared Tumor Antigen: T Cell Responses to Antigenic Peptides Translated from Different Open Reading Frames
Rongfu Wang,Samuel L. Johnston,Gang Zeng,Suzanne L. Topalian,Douglas J. Schwartzentruber,Steven A. Rosenberg +5 more
TL;DR: It is reported that screening a cDNA library from the 586mel cell line using CTL clones derived from TIL586 resulted in the isolation of a gene, CAG-3 (cancer Ag gene 3).
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CD4+ T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA DP4 allele: Association with NY-ESO-1 antibody production
TL;DR: Results suggested that NY-ESO-1-specific DP4-restricted CD4+ T cells were closely associated with NY- ESO-2-specific Ab observed in melanoma patients and might play an important role in providing help for activating B cells for NY-esO- 1- specific Ab production.
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HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells
TL;DR: The presence of mRNA and protein expression in 43 primary glioblastoma multiforme cell lines and 7 established human GBM cell lines is characterized to indicate that HER-2, gp100, and MAGE-1 could be used as tumor antigen targets for surrogate assays for antigen-specific CTLs or to develop antigen- specific active immunotherapy strategies for glioma patients.