Garazi Serna

TL;DR: Col colonization of human colorectal cancers with Fusobacterium and its associated microbiome—including Bacteroides, Selenomonas, and Prevotella species—is maintained in distal metastases, demonstrating microbiome stability between paired primary and metastatic tumors.

TL;DR: In this article , a large-scale functional screen of dual-targeting bispecific antibodies (bAbs) on a heterogeneous colorectal cancer PDO biobank and paired healthy colonic mucosa samples was described.

TL;DR: In this article, a humanized antagonistic CD73 antibody, mAb19, with distinct binding properties was identified, which can effectively inhibit the enzymatic activity of CD73 in vitro, resulting in an inhibition of adenosine formation and enhanced T-cell activation.

TL;DR: In this paper, the authors analyzed the distribution of CD2AP in the AD brain and its potential associations with tau aggregation and β-amyloid (Aβ) deposition.

TL;DR: In this article , the V3-V4 region of the 16S rRNA gene was sequenced using Illumina MiSeq platform and the output obtained from the sequencing was analysed by diversity (alfa diversity with Shannon index and Beta diversity with Bray-Curtis) and taxonomic (Linear Discriminant Analysis (LDA)) analyses.