G
Gathsaurie Neelika Malavige
Researcher at University of Sri Jayewardenepura
Publications - 154
Citations - 3760
Gathsaurie Neelika Malavige is an academic researcher from University of Sri Jayewardenepura. The author has contributed to research in topics: Dengue fever & Dengue virus. The author has an hindex of 30, co-authored 127 publications receiving 2974 citations. Previous affiliations of Gathsaurie Neelika Malavige include University of Oxford & University of Nottingham.
Papers
More filters
Journal ArticleDOI
Dengue viral infections
TL;DR: This review outlines aspects of the epidemiology of d Dengue infections, the dengue virus and its mosquito vector, clinical features and pathogenesis of denge infections, and the management and control of these infections.
Journal ArticleDOI
Pathogenesis of liver involvement during dengue viral infections
TL;DR: Clinical and experimental observations that suggest that liver involvement occurs during dengue infections are described and the possible role played by host immune responses in this process is outlined.
Journal ArticleDOI
Pathogenesis of vascular leak in dengue virus infection.
TL;DR: Endothelial dysfunction leading to vascular leak is the hallmark of severe dengue, suggesting that it is likely to occur as a result of inflammatory mediators, rather than infection of the endothelium, and drugs that block down‐stream immunological mediator pathways such as PAF may also be beneficial in the treatment of severe disease.
Journal ArticleDOI
Patterns and causes of liver involvement in acute dengue infection
Samitha Fernando,Ananda Wijewickrama,Laksiri Gomes,C Punchihewa,S. D. P. Madusanka,Harsha Dissanayake,Chandima Jeewandara,Hemantha Peiris,Graham S. Ogg,Gathsaurie Neelika Malavige,Gathsaurie Neelika Malavige +10 more
TL;DR: Dengue associated liver injury appears to peak around day 6 and 7 of illness, and liver function tests done at earlier dates might not reflect the extent of liver involvement in acute infection.
Journal ArticleDOI
Patterns of disease among adults hospitalized with dengue infections
Gathsaurie Neelika Malavige,V. G.N.S. Velathanthiri,Eranga S Wijewickrama,Sirimali Fernando,S D Jayaratne,John Aaskov,Suranjith L. Seneviratne +6 more
TL;DR: These adults showed differences in clinical and laboratory findings, disease severity and mortality, compared to children seen during the same epidemic, as well as pooling data on adult dengue patients from different regions to understand the natural history of disease in this group.