G
Gavin C. Donaldson
Researcher at National Institutes of Health
Publications - 200
Citations - 20840
Gavin C. Donaldson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: COPD & Exacerbation. The author has an hindex of 61, co-authored 185 publications receiving 18944 citations. Previous affiliations of Gavin C. Donaldson include Queen Mary University of London & Imperial College London.
Papers
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Journal ArticleDOI
Cardiovascular Risk, Myocardial Injury, and Exacerbations of Chronic Obstructive Pulmonary Disease
Anant R.C. Patel,Beverly Kowlessar,Gavin C. Donaldson,Alexander J. Mackay,Richa Singh,SN George,Davinder S. Garcha,Jadwiga A. Wedzicha,John R. Hurst +8 more
TL;DR: Frequent COPD exacerbations and exacerbation frequency impact cardiovascular risk and myocardial injury, and whether this is related to airway infection and inflammation, and frequent exacerbators have greater arterial stiffness than infrequent exacerbators.
Journal ArticleDOI
Human rhinovirus infection during naturally occurring COPD exacerbations
SN George,Davinder S. Garcha,Alexander J. Mackay,Anant R.C. Patel,Richa Singh,Raymond J. Sapsford,Gavin C. Donaldson,Jadwiga A. Wedzicha +7 more
TL;DR: HRV prevalence and load increased at COPD exacerbation, and resolved during recovery, and Frequent exacerbators were more likely to experience HRV infection.
Journal ArticleDOI
The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development.
James P. Allinson,Rebecca Hardy,Gavin C. Donaldson,Seif O. Shaheen,Diana Kuh,Jadwiga A. Wedzicha +5 more
TL;DR: Smoking-related CMH usually resolves following smoking cessation but the longer its duration the greater the FEV1 lost, suggesting the course of CMH across adult life may reflect the underlying course of airway disease activity.
Journal ArticleDOI
Relationships among bacteria, upper airway, lower airway, and systemic inflammation in COPD.
TL;DR: COPD is associated with an increased nasal concentration of the neutrophil chemoattractant protein IL-8, the degree of which reflects that present in the lower airway, and a relationship between lowerAirway bacterial colonization, postnasal drip, and higher nasal bacterial load may suggest a mechanism underlying this finding.
Journal ArticleDOI
Determinants and impact of fatigue in patients with chronic obstructive pulmonary disease
R Baghai-Ravary,Jennifer K Quint,James J.P. Goldring,John R. Hurst,Gavin C. Donaldson,Jadwiga A. Wedzicha +5 more
TL;DR: The perception of fatigue increased in patients with COPD compared to age-matched control subjects, and associated with morbidity when patients were stable and at exacerbation.