G
Gennaro Galizia
Researcher at Seconda Università degli Studi di Napoli
Publications - 112
Citations - 5081
Gennaro Galizia is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 38, co-authored 107 publications receiving 4613 citations. Previous affiliations of Gennaro Galizia include University of Naples Federico II & University of Edinburgh.
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Journal ArticleDOI
Treatment of gastric cancer.
Michele Orditura,Gennaro Galizia,Vincenzo Sforza,Valentina Gambardella,Alessio Fabozzi,Maria Maddalena Laterza,F Andreozzi,Jole Ventriglia,B. Savastano,Andrea Mabilia,Eva Lieto,Fortunato Ciardiello,Ferdinando De Vita +12 more
TL;DR: Recent evidence supports the use of second-line chemotherapy after progression in patients with good performance status, and perioperative and adjuvant chemotherapy, as well as chemoradiation, can improve outcome of resectable gastric cancer with extended lymph node dissection.
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Expression of Vascular Endothelial Growth Factor (VEGF) and Epidermal Growth Factor Receptor (EGFR) is an Independent Prognostic Indicator of Worse Outcome in Gastric Cancer Patients
Eva Lieto,Francesca Ferraraccio,Michele Orditura,Paolo Castellano,Anna La Mura,Margherita Pinto,Anna Zamboli,Ferdinando De Vita,Gennaro Galizia +8 more
TL;DR: Evidence is provided that contemporary evaluation of VEGF and EGFR expression may be crucial to select gastric cancer patients with poor prognosis who may benefit of tailored treatments.
Journal ArticleDOI
Prognostic significance of circulating IL-10 and IL-6 serum levels in colon cancer patients undergoing surgery.
Gennaro Galizia,Michele Orditura,Ciro Romano,Eva Lieto,Paolo Castellano,Pelosio L,Vincenzo Imperatore,Giuseppe Catalano,Carlo Pignatelli,Ferdinando De Vita +9 more
TL;DR: Preoperative serum levels ofIL-10 were shown to be useful markers for predicting both likelihood to perform curative surgery and, in combination with the 16th postoperative day IL-10 serum levels, tumor recurrence (predictive accuracy, 73.6 and 96%, respectively).
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Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients.
Tian Li Wang,Luis A. Diaz,Katharine E. Romans,Alberto Bardelli,Saurabh Saha,Gennaro Galizia,Michael A. Choti,Ross C. Donehower,Giovanni Parmigiani,Ie Ming Shih,Christine A. Iacobuzio-Donahue,Kenneth W. Kinzler,Bert Vogelstein,Christoph Lengauer,Victor E. Velculescu +14 more
TL;DR: It is suggested that genetic amplification of TYMS is a major mechanism of 5-FU resistance in vivo and have important implications for the management of colorectal cancer patients with recurrent disease.
Journal ArticleDOI
Counting alleles to predict recurrence of early-stage colorectal cancers.
Wei Zhou,Wei Zhou,Steven N. Goodman,Gennaro Galizia,Eva Lieto,Francesca Ferraraccio,Carlo Pignatelli,Colin A. Purdie,J Piris,Robert H Morris,David J. Harrison,Philip B. Paty,Al Culliford,Katharine E. Romans,Elizabeth A. Montgomery,Michael A. Choti,Kenneth W. Kinzler,Bert Vogelstein,Bert Vogelstein +18 more
TL;DR: In patients without metastasis, allelic imbalance is a better predictor of prognosis than histopathological stage.