G
Georgia Sotiropoulou
Researcher at RMIT University
Publications - 105
Citations - 4907
Georgia Sotiropoulou is an academic researcher from RMIT University. The author has contributed to research in topics: Kallikrein & Cancer. The author has an hindex of 38, co-authored 97 publications receiving 4589 citations. Previous affiliations of Georgia Sotiropoulou include Mount Sinai Hospital, Toronto & University of Patras.
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Journal ArticleDOI
A novel theranostic activity-based probe targeting kallikrein 7 for the diagnosis and treatment of skin diseases.
Evangelos Bisyris,Eleni Zingkou,Golfo G. Kordopati,Minos-Timotheos Matsoukas,Plato A. Magriotis,Georgios Pampalakis,Georgia Sotiropoulou +6 more
TL;DR: In this paper, a new in silico approach for using protease-substrate motifs to design a kallikrein 7 (KLK7)-specific phosphonate activity-based probe (ABP) was applied to quantify the active KLK7 in situ.
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Cocktails of KLK5 Protease Inhibitors and Anti-TNFα Therapeutics: an Effective Treatment for Netherton Syndrome
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Reconstructing the epidermal proteolytic cascades in health and disease
TL;DR: How epidermal proteolysis is finely regulated at multiple levels, and in a spatial manner that has not been taken into consideration so far, is elaborate, to provide an up‐to‐date critical evaluation and synthesis of current knowledge and the extended complexity of proteolytic regulation and signaling pathways in skin.
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Activity-Based Probes for Proteases Pave the Way to Theranostic Applications
TL;DR: Activity-based probes act as suicide inhibitors of proteases, which can be exploited for delineation of the functional role(s) of a given protease in (patho) biological context and as potential therapeutics, and represent new theranostic agents.
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Effects of secondary ice processes on a stratocumulus to cumulus transition during a cold-air outbreak
Michail Karalis,Georgia Sotiropoulou,Steven J. Abel,E. Bossioli,Paraskevi Georgakaki,Georgia Methymaki,Athanasios Nenes,Maria Tombrou +7 more
TL;DR: In this article , the authors used the Weather Research and Forecasting model to investigate the impact of the most well-known SIP mechanisms (Hallett-Mossop, mechanical break-up upon collisions between ice particles and drop-shattering) on a CAO case observed north of the United Kingdom in 2013.