G
Gerald W. Dorn
Researcher at Cincinnati Children's Hospital Medical Center
Publications - 3
Citations - 2202
Gerald W. Dorn is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Transgene & Electrical conduction system of the heart. The author has an hindex of 2, co-authored 3 publications receiving 2073 citations.
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Journal ArticleDOI
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
Christopher P. Baines,Robert A. Kaiser,Nicole H. Purcell,N. Scott Blair,Hanna Osinska,Michael Hambleton,Eric W. Brunskill,M. Richard Sayen,Roberta A. Gottlieb,Gerald W. Dorn,Jeffrey Robbins,Jeffery D. Molkentin +11 more
TL;DR: Cyclophilin D and the mitochondrial permeability transition are required for mediating Ca2+- and oxidative damage-induced cell death, but not Bcl-2 family member-regulated death.
Journal ArticleDOI
Physiological Growth Synergizes With Pathological Genes in Experimental Cardiomyopathy
Faisal Syed,Amy Odley,Harvey S. Hahn,Eric W. Brunskill,Roy A. Lynch,Yehia Marreez,Atsushi Sanbe,Jeffrey Robbins,Gerald W. Dorn +8 more
TL;DR: Normal postnatal cardiac growth can be an essential cofactor in development of genetic cardiomyopathies, and may confound the interpretation of conventional &agr;-MHC transgenic phenotypes.
Listening for hoof beats in heart beats Disruption of the Sp1-related transcription factor HF-1b leads to alterations in the cardiac conduction system that result in ventricular arrhythmias and sudden death. What does this tell us about how ventricular cardiomyocytes differentiate into the specialized cells that form the heart's conductance system?
Jeffrey Robbins,Gerald W. Dorn +1 more