G
Gerard Pardo
Researcher at Carlos III Health Institute
Publications - 8
Citations - 1502
Gerard Pardo is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Adipose tissue & White adipose tissue. The author has an hindex of 8, co-authored 8 publications receiving 1306 citations.
Papers
More filters
Journal ArticleDOI
Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance
José María Moreno-Navarrete,Francisco J. Ortega,Marta Serrano,Ester Guerra,Gerard Pardo,Francisco J. Tinahones,Wifredo Ricart,José Manuel Fernández-Real +7 more
TL;DR: Investigation of FNDC5 gene expression in human muscle and adipose tissue and circulating irisin according to obesity, insulin sensitivity, and type 2 diabetes suggests a loss of brown-like characteristics and a potential target for therapy.
Journal ArticleDOI
MiRNA expression profile of human subcutaneous adipose and during adipocyte differentiation.
Francisco J. Ortega,José María Moreno-Navarrete,Gerard Pardo,Mònica Sabater,Manuela Hummel,Anna Ferrer,José Ignacio Rodríguez-Hermosa,Bartomeu Ruiz,Wifredo Ricart,Belén Peral,José Manuel Fernández-Real +10 more
TL;DR: The remarkable inverse miRNA profile revealed for human pre-adipocytes and mature adipocytes hints at a closely crosstalk between miRNAs and adipogenesis.
Journal ArticleDOI
Circulating lipopolysaccharide-binding protein (LBP) as a marker of obesity-related insulin resistance
J M Moreno-Navarrete,F Ortega,Matteo Serino,Elodie Luche,Aurélie Waget,Gerard Pardo,Javier Salvador,Wifredo Ricart,Gema Frühbeck,Rémy Burcelin,José Manuel Fernández-Real +10 more
TL;DR: LBP is an inflammatory marker associated with obesity-related insulin resistance and was significantly associated with insulin sensitivity and different inflammatory markers and decreased after weight loss in association with changes in body mass index and insulin sensitivity.
Journal ArticleDOI
A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction.
José María Moreno-Navarrete,Xavier Escoté,Francisco Ortega,Matteo Serino,Mark Campbell,Marie-Caroline Michalski,Martine Laville,Gemma Xifra,Elodie Luche,Pere Domingo,Mònica Sabater,Gerard Pardo,Aurélie Waget,Javier Salvador,Marta Giralt,José Ignacio Rodríguez-Hermosa,Marta Camps,Catherine Ines Kolditz,Nathalie Viguerie,Jean Galitzky,Pauline Decaunes,Wifredo Ricart,Gema Frühbeck,Francesc Villarroya,Geltrude Mingrone,Dominique Langin,Antonio Zorzano,Hubert Vidal,Joan Vendrell,Rémy Burcelin,Antonio Vidal-Puig,José Manuel Fernández-Real +31 more
TL;DR: Functionally, LBP knockdown using short hairpin (sh)RNA or anti-LBP antibody led to increases in markers of adipogenesis and decreased adipocyte inflammation in human adipocytes.
Journal ArticleDOI
OCT1 Expression in Adipocytes Could Contribute to Increased Metformin Action in Obese Subjects
José María Moreno-Navarrete,Francisco Ortega,José-Ignacio Rodríguez-Hermosa,Mònica Sabater,Gerard Pardo,Wifredo Ricart,José Manuel Fernández-Real +6 more
TL;DR: Investigation of the gene expression and protein levels of OCT-1 and OCT-2 in adipose tissue and during adipogenesis and their possible role in metformin action on adipocytes concluded that increased OCT1 gene expression in adipOSE tissue of obese subjects might contribute to increased met formin action in these subjects.