Gian F. Gensini

TL;DR: The present study shows that during aortic surgery, the genes for interleukin-6 and for the components of the local renin-angiotensin system are activated early in the ischemic muscle, and activation persists during reperfusion, and the occurrence of systemic inflammatory reaction with increased interleuko-6 plasma concentrations is followed by impaired pulmonary function.

TL;DR: Findings indicate that TxB2 and PGI2 formation may represent a modulating mechanism of vascular response to adrenergic stimulation.

TL;DR: In human nonfailing myocytes, high glucose allows Ang II to activate JAK2 signaling, whereas in failing myocyte, hyperglycemia alone is able to induce Ang II generation, which in turn activates Jak2 via enhanced oxidative stress.

TL;DR: Examination of existing evidence concerning inclusion and exclusion criteria, and outcomes (in-hospital and long-term mortality rates and neurological recovery) in studies performed in patients with refractory CA treated with ECMO suggests that in CA patients, ECMO is a highly costly intervention and optimal utilization requires a dedicated local health-care organization and expertise in the field.

TL;DR: The weather considered as a combination of different weather variables may affect BP and the forecast of a sudden change of AM could provide important information helpful for hypertensives during winter.