G
Gideon Almogy
Researcher at Hebrew University of Jerusalem
Publications - 7
Citations - 1346
Gideon Almogy is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Fusobacterium nucleatum & Fusobacteria. The author has an hindex of 5, co-authored 6 publications receiving 854 citations.
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Journal ArticleDOI
Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack.
Chamutal Gur,Yara Ibrahim,Batya Isaacson,Rachel Yamin,Jawad Abed,Moriya Gamliel,Jonatan Enk,Yotam Bar-On,Noah Stanietsky-Kaynan,Shunit Coppenhagen-Glazer,Noam Shussman,Gideon Almogy,Angelica Cuapio,Erhard Hofer,Dror Mevorach,Adi Tabib,Rona Ortenberg,Gal Markel,Karmela Miklić,Stipan Jonjić,Caitlin A. Brennan,Wendy S. Garrett,Gilad Bachrach,Ofer Mandelboim +23 more
TL;DR: This work has shown that natural killer cell killing of various tumors is inhibited in the presence of various F. nucleatum strains, and identified a bacterium-dependent, tumor-immune evasion mechanism in which tumors exploit the Fap2 protein of F. nucleus to inhibit immune cell activity via TIGIT.
Journal ArticleDOI
Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc.
Jawad Abed,Johanna E. M. Emgård,Gideon Zamir,Mouhammad Faroja,Gideon Almogy,Amalie Grenov,Asaf Sol,Ronit Naor,Eli Pikarsky,Karine Atlan,Anna Mellul,Stella Chaushu,Abigail L. Manson,Ashlee M. Earl,Nora Ou,Caitlin A. Brennan,Wendy S. Garrett,Gilad Bachrach +17 more
TL;DR: A host polysaccharide and fusobacterial lectin that explicates fusObacteria abundance in CRC is identified and targeting F. nucleatum Fap2 or host epithelial Gal-GalNAc may reduce fusOBacteria potentiation of CRC.
Journal ArticleDOI
Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System.
Jawad Abed,Naseem Maalouf,Abigail L. Manson,Ashlee M. Earl,Lishay Parhi,Johanna E. M. Emgård,Michael Klutstein,Shay Tayeb,Gideon Almogy,Karine Atlan,Stella Chaushu,Eran Israeli,Ofer Mandelboim,Wendy S. Garrett,Wendy S. Garrett,Gilad Bachrach +15 more
TL;DR: In this paper, the authors performed whole genome sequencing of paired, same-patient oral and colorectal adenomas (CRC) Fusobacterium nucleatum isolates and confirmed that CRC-fusobacteria originate from the oral microbial reservoir.
Journal ArticleDOI
Intra-arterial thrombolysis and stent placement for traumatic carotid dissection with subsequent stroke: a combined, simultaneous endovascular approach.
José E. Cohen,John M. Gomori,Savvas Grigoriadis,Ram Elazary,Gideon Almogy,Gideon Zamir,Avraham Y. Rivkind,Aved Khalaileh +7 more
TL;DR: Combined, simultaneous intra-arterial fibrinolysis and carotid stenting through a bilateral approach was successfully performed allowing the complete clinical recovery of the patient, and this approach was proved to be safe and effective.
Journal ArticleDOI
Patient Self-Assessment of Surgical Site Infection is Inaccurate
TL;DR: Self-assessment strategies in order to fulfill 30-day SSI surveillance misestimate SSI rates and lead to an erroneous overall appreciation of inter-institutional variation, which is proposed to be abandoned.