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Gideon Goldstein
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 170
Citations - 15646
Gideon Goldstein is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Thymopoietin & T cell. The author has an hindex of 59, co-authored 170 publications receiving 15479 citations. Previous affiliations of Gideon Goldstein include Weizmann Institute of Science & Necker-Enfants Malades Hospital.
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Journal ArticleDOI
Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage
TL;DR: It is suggested that is it now possible to define stages of T-cell differentiation that can be related to T- cell malignancies in humans.
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Monoclonal antibodies defining distinctive human T cell surface antigens
TL;DR: Three novel nonoclonal antibodies (designed OKT1, OKT3, and OKT4) were generated against surface determinants of human peripheral T cells but differed in their reactivities with T cel- lines.
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Separation of functional subsets of human T cells by a monoclonal antibody.
TL;DR: OKT4 could be a valuable reagent for determining alterations of these functional subsets in human diseases and suggest that the OKT4+ subset represents a helper population and that the OkT4- subset contains the cytotoxic effector population.
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Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells
Gideon Goldstein,Margrit P. Scheid,Ulrich Hämmerling,David H. Schlesinger,Hugh D. Niall,Edward A. Boyse +5 more
TL;DR: This polypeptide shows a high degree of evolutionary conservation, exhibiting close structural, functional, and immunological similarity when isolated from such diverse origins as cells of mammals and higher plants, and so may well be a universal constituent of living cells.
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Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies.
Samuel D. Wright,P E Rao,W. C. Van Voorhis,Lydia S. Craigmyle,K Iida,M A Talle,E F Westberg,Gideon Goldstein,Samuel C. Silverstein +8 more
TL;DR: The C3bi receptor of human M phi is a complex composed of two polypeptides, Mr 185,000 and 105,000, and monoclonal antibodies reacting with four distinct antigenic determinants of this complex are identified.