Giovanna Baron

TL;DR: The disulphide breaking activity of NAC also explains its mucolytic activity which is due to its effect in reducing heavily cross-linked mucus glycoproteins and free thiols as well as reduced proteins which have important direct antioxidant activity.

TL;DR: The present review reports and discusses the most recent studies on the molecular mechanisms of carnosine which need to be fully clarified before promoting carnosines and derivatives as therapeutic agents.

TL;DR: ALs derived from lipid peroxidation derived reactive carbonyl species (RCS) are binders of RAGE and this affinity depends on the effect of the adduct moiety to reduce the basicity of the target amino acid and on the acid moieties surrounding the aminoacidic target.

TL;DR: It can be concluded that nutritionally relevant doses of synthesized anserine are well-absorbed and that its degradation by serum carnosinase-1 is less pronounced compared to carnosine, which makes anSerine a good candidate as a more stable carnosinesine-analogue to attenuate chronic diseases in humans.

TL;DR: The semiquantitative analysis revealed the presence of high‐abundance class of proteins, such as larval storage protein (LSP) class, and proved the potential industrial applications of Bombyx mori pupae, as source of high-value proteins in a green and “circular” economy perspective.